加热卷烟添加剂研究进展  

Research progress on tobacco additives in heated tobacco products

作　　者：李奕蓉 朱瑞芝 刘春波 唐石云 蒋薇 李振杰 蒋丽红[1] 杨继 LI Yirong;ZHU Ruizhi;LIU Chunbo;TANG Shiyun;JIANG Wei;LI Zhenjie;JIANG Lihong;YANG Ji(School of Chemistry Engineering,Kunming University of Technology,Kunming 650500,China;Yunnan Key Laboratory of Tobacco Chemistry,Technology Center of China Tobacco Yunnan Industrial Co.,Ltd.,Kunming 650231,China)

机构地区：[1]昆明理工大学化学工程学院,昆明市650500 [2]云南省烟草化学重点实验室云南中烟工业有限责任公司技术中心,昆明市650231

出　　处：《烟草科技》2023年第4期104-112,共9页Tobacco Science & Technology

基　　金：云南中烟工业有限责任公司科技开发计划“加热卷烟添加剂安全性评价技术研究及数字化平台构建”(2021JC05);国家烟草专卖局重大专项项目“卷烟燃烧段全组分热特性多维数据集的构建及应用”[110202201054(SJ-04)]。

摘　　要：为了掌握近年来国内外加热卷烟添加剂的研究现状,参考国外烟草公司对添加剂的安全性评估规程,对添加剂的使用要求、热解行为、对烟气的影响以及毒理学评估等方面进行了综述。结果表明:(1)大多数加热卷烟添加剂在受热温度低于350℃时以原型转移至烟气中,但受化合物本身性质以及裂解氛围等的影响,裂解产物分布略有差异。(2)添加剂能在低温状态下促进烟气中烟碱、甘油和香味成分等关键物质的释放,添加特定的硅酸盐能够降低有害成分的释放。(3)现有添加剂毒理学研究中,常用的甘油、丙二醇和薄荷醇等添加剂在加热状态下不会增加主流烟气的细胞毒性,但在是否能降低烟气毒性方面还需作进一步探索。To understand the current status of research on additives used in tobacco sticks for heated tobacco products at home and abroad in recent years,the requirements for use of additives,the pyrolysis behavior and the toxicological assessment of additives,and the effects of additives on smoke were reviewed with reference to the safety assessment protocols for additives used by foreign tobacco companies.The conclusions were as follows:1)Most of the heated tobacco product additives were transferred to the smoke in their original form when heated below 350℃.However,the distribution of the pyrolysis products of the additives varied slightly depending on the structural properties of the compounds themselves and the pyrolysis atmosphere,and other factors.2)Additives could promote the releases of key compounds,such as nicotine,glycerin,and aroma components in the smoke at lower temperatures,and the addition of specific silicates could reduce the releases of harmful components.3)In the existing additive toxicology studies,commonly used additives,such as glycerin,propylene glycol,and menthol did not increase the cytotoxicity of mainstream smoke in the heated state,but further research should be conducted to determine whether they could reduce smoke toxicity.

关 键 词：加热卷烟 添加剂 安全性评估规程 热解 毒理学评估 热裂解-气相色谱-质谱联用法 烟气调控 

分 类 号：TS47[农业科学—烟草工业]