Nerve function restoration following targeted muscle reinnervation after varying delayed periods  

作　　者：Yuanheng Li Jiangping Huang Yuling Chen Shanshan Zhu Zhen Huang Lin Yang Guanglin Li 

机构地区：[1]Key Laboratory of Human-Machine Intelligence-Synergy Systems and Branch of Shenzhen Institute of Artificial Intelligence and Robotics for Society,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong Province,China [2]Department of Rehabilitation Medicine,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong Province,China [3]Department of Rehabilitation Medicine,Yibin Hospital of Traditional Chinese Medicine,Yibin,Sichuan Province,China

出　　处：《Neural Regeneration Research》2023年第12期2762-2766,共5页中国神经再生研究（英文版）

基　　金：supported in part by the National Natural Science Foundation of China,Nos.U1913601,81927804;the Key-Area Research and Development Program of Guangdong Province,No.2020B0909020004(GL);the National Natural Science Foundation of China,Nos.81960419,82260456(both to LY)。

摘　　要：Targeted muscle reinnervation has been proposed for reconstruction of neuromuscular function in amputees.However,it is unknown whether performing delayed targeted muscle reinnervation after nerve injury will affect restoration of function.In this rat nerve injury study,the median and musculocutaneous nerves of the forelimb were transected.The proximal median nerve stump was sutured to the distal musculocutaneous nerve stump immediately and 2 and 4 weeks after surgery to reinnervate the biceps brachii.After targeted muscle reinnervation,intramuscular myoelectric signals from the biceps brachii were recorded.Signal amplitude gradually increased with time.Biceps brachii myoelectric signals and muscle fiber morphology and grooming behavior did not significantly differ among rats subjected to delayed target muscle innervation for different periods.Targeted muscle reinnervation delayed for 4 weeks can acquire the same nerve function restoration effect as that of immediate reinnervation.

关 键 词：biceps brachii delayed nerve repair delayed targeted muscle reinnervation functional reconstruction grooming test implanted electrode intramuscular myoelectric signals median nerve motor function nerve transfer 

分 类 号：R622[医药卫生—整形外科]