二维纳米材料MXenes在组织工程中的应用  

Application of two-dimensional nanomaterial MXenes in tissue engineering

作　　者：周洪玲 吴也可[2] 赵立星[1] ZHOU Hongling;WU Yeke;ZHAO Lixing(State Key Laboratory of Oral Diseases,National Clinical Research Center for Oral Diseases,Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;Department of Stomatology,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China)

机构地区：[1]口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医院正畸科,四川省成都市610041 [2]成都中医药大学附属医院口腔科,四川省成都市610072

出　　处：《组织工程与重建外科》2023年第2期178-183,共6页Journal of Tissue Engineering and Reconstructive Surgery

基　　金：国家自然科学基金项目(81973684,31670992)。

摘　　要：过渡金属碳化物、氮化物或碳氮化物(MXenes)作为一种新型的二维材料,具有高电导率、亲水性、高比表面积、良好的机械强度和光热转换性能等优点,在生物医学领域,尤其是组织工程领域,具有重要的潜在应用价值。本文总结MXenes生物相容性的研究进展,重点介绍MXenes在骨修复、皮肤再生等组织工程领域的应用,并阐述MXenes在组织工程应用中所面临的挑战及其潜在的研究方向,以期对MXenes在组织工程中的研究及临床应用提供帮助。Owing to the advantages of high conductivity,hydrophilicity,high specific surface area,fascinating mechanical strength and photothermal conversion performance,transition metal carbides,nitrides or carbonitrides(MXenes),as a new kind of two-dimensional materials,have shown remarkable potential applications in the field of biomedicine,especially in tissue engineering.In this paper,the research progress of biocompatibility of MXenes was briefly summarized,the application of MXenes in tissue engineering such as bone repair and skin regeneration was emphatically introduced,and finally the challenges and potential research directions of MXenes in tissue engineering were prospected,aiming to provide some insights for the research and clinical application of MXenes in tissue engineering.

关 键 词：过渡金属碳化物、氮化物或碳氮化物 生物相容性 骨再生 皮肤再生 

分 类 号：R318.08[医药卫生—生物医学工程]