骨髓间充质干细胞治疗激素性股骨头坏死的研究进展  

Research progress on bone marrow mesenchymal stem cells in the treatment of steroid-induced osteonecrosis of femoral head

作　　者：钱士达 于雪峰[1] QIAN Shida;YU Xuefeng(Department of Orthopedics,Fourth Affiliated Hospital of Nanchang University,Nanchang 330003,China)

机构地区：[1]南昌大学第四附属医院骨科,330003

出　　处：《天津医药》2023年第5期553-556,共4页Tianjin Medical Journal

基　　金：国家自然科学基金项目(82174190)。

摘　　要：激素性股骨头坏死的病因和发生机制尚未完全阐明,且缺乏有效的治疗方法。随着干细胞治疗技术在各大学科的应用,许多学者开始研究干细胞的性质和功能,并应用于激素性股骨头坏死的治疗中。单纯的干细胞移植效果不佳,但对干细胞进行移植前修饰可以提高其疗效。该文就骨髓间充质干细胞治疗激素性股骨头坏死的研究进展进行综述。The etiology and mechanism of steroid-induced osteonecrosis of femoral head(SONFH)have not been fully elucidated,and effective treatments have not yet emerged.With the application of stem cell therapy technology in various disciplines,the nature and function of stem cells have been extensively studied and applied in the treatment of SONFH.However,stem cell transplantation alone is not effective,and its efficacy can be enhanced by pretransplantation modification.This paper reviews the research progress of bone marrow mesenchymal stem cells in the treatment of SONFH.

关 键 词：股骨头坏死 间质干细胞 干细胞移植 激素性股骨头坏死 骨髓间充质干细胞 

分 类 号：R681.802[医药卫生—骨科学]