外周动静脉换血技术在新生儿疾病中的应用  

Application of peripheral arteriovenous exchange transfusion in neonatal diseases

作　　者：马汇擎 刘洋[1] MA Huiqing;LIU Yang(Department of Neonatology,Tianjin Children's Hospital/Tianjin University Children's Hospital,Tianjin 300134,China;Graduate College,Tianjin Medical University)

机构地区：[1]天津市儿童医院/天津大学儿童医院新生儿内科,300134 [2]天津医科大学研究生院

出　　处：《天津医药》2023年第5期556-560,共5页Tianjin Medical Journal

基　　金：天津市科技计划项目(21JCYBJC00370);天津市卫生健康科技项目(ZC20120);天津市自然科学基金(21JCZDJC01030);天津市医学重点学科(专科)建设项目资助(TJYXZDXK-040A)。

摘　　要：外周动静脉换血技术作为一项能够快速救治危重新生儿的治疗手段,常用于新生儿高胆红素血症和新生儿同族免疫性溶血的治疗。通过检索国内外采用换血技术治疗新生儿疾病的相关文献,总结了该技术在新生儿败血症、新生儿贫血、新生儿中毒等常见疾病,以及妊娠期同种免疫性肝病、暂时性骨髓增生性疾病、有机酸血/尿症等较罕见疾病中的应用。并阐明该技术在相关疾病中的应用原理、治疗效果及新生儿的不良反应,以期为上述相关疾病的治疗提供补充的选择。Peripheral arteriovenous exchange transfusion,as a rapid treatment for critical neonates,has been widely utilized in the treatment of neonatal hyperbilirubinemia and neonatal alloimmune hemolysis.Based on domestic and foreign literature review on neonatal diseases treated with exchange transfusion technique,the application of this treatment in common diseases such as neonatal sepsis,neonatal anemia and neonatal poisoning,as well as rare diseases such as gestational alloimmune liver disease,transient abnormal myelopoiesis and organic acidurias is summarized.The application principle of this technique in related diseases,therapeutic effect and adverse reactions of neonates are also expounded,in order to provide a supplementary choice for the treatment of these diseases.

关 键 词：交换输血 全血 婴儿 新生 高胆红素血症 新生儿 贫血 溶血性 自身免疫性 新生儿败血症 

分 类 号：R722.1[医药卫生—儿科]