益生菌在儿童尿路感染中的研究进展  

Research progress of probiotics in children with urinary tract infection

作　　者：杨琴 YANG Qin(Department of Pediatric Nephrology,the Affiliated Women’s and Children’s Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu Women’s and Children’s Central Hospital,Sichuan Province,Chengdu 611731,China)

机构地区：[1]电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院儿童肾脏内科,四川成都611731

出　　处：《妇儿健康导刊》2023年第8期36-39,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：尿路感染是儿童常见的感染性疾病,由于儿童特有的解剖生理特点,其发病率及复发率均较成人高。抗生素是治疗儿童尿路感染最主要的方式。但随着抗生素的广泛使用,全球范围内细菌耐药率逐渐升高。近年来,有学者发现益生菌作为一种辅助治疗方式可以使尿路感染患儿受益,其主要作用机制包括维持黏膜屏障功能、抵抗定植菌侵袭、灭活细菌毒素和致病因子等。因此,益生菌有望成为非抗生素途径预防儿童尿路感染的一种方式。本文对益生菌在儿童尿路感染中的研究进展作一综述。Urinary tract infection is common infectious diseases in children,and its incidence and recurrence rates are higher than those of adults due to the unique anatomical and physiological characteristics of children.Antibiotics are the most prominent way to treat urinary tract infection in children,but with the widespread use of antibiotics,the rate of bacterial resistance is gradually increasing worldwide.In recent years,probiotics have been found to benefit children with urinary tract infection as an adjunctive treatment modality,and their main mechanisms of action include maintenance of mucosal barrier function,resistance to colonizing bacteria,inactivation of bacterial toxins and pathogenic factors,etc.Therefore,probiotics are expected to be a non-antibiotic way to prevent urinary tract infection in children.This article reviews the research progress of prob iotics in urinary tract infection.

关 键 词：尿路感染 益生菌 儿童 

分 类 号：R726.9[医药卫生—儿科]