化痰活血方外用治疗膝骨关节炎临床观察  

Clinical Observation on External Application of Eliminating Phlegm and Promoting Blood Circulation Prescription in Treating Knee Osteoarthritis

作　　者：田瑶 周源 庄宛滢 彭荣立 李云 刘瑶 TIAN Yao;ZHOU Yuan;ZHUANG Wanying;PENG Rongli;LI Yun;LIU Yao(Department of Traditional Chinese Medicine,Hepingli Community Health Service Center,Beijing 100013,China;General Department,Dongcheng District Community Health Service Center,Beijing 100010,China)

机构地区：[1]北京市东城区和平里社区卫生服务中心中医科,北京100013 [2]北京市东城区社区卫生服务管理中心全科,北京100010

出　　处：《中国中医药现代远程教育》2023年第9期106-109,共4页Chinese Medicine Modern Distance Education of China

基　　金：北京市中医管理局北京中医药高层次人才扎根基层五联动示范工程【No.2018-01】;北京市东城区卫生科技计划项目【No.东卫健研〔2020〕-13】。

摘　　要：目的观察化痰活血方局部外用治疗膝骨关节炎的临床效果。方法采用单中心、随机对照、双盲的研究方法,将患者分为试验组和对照组。试验组外用化痰活血方配合电脑中频治疗,对照组外用安慰剂配合电脑中频治疗。比较2组疗效、视觉模拟量表(VAS)评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分及安全性。结果2组治疗前后VAS评分比较,差异具有统计学意义(P<0.05);组内比较,试验组和对照组治疗前后差异有统计学意义(均P<0.001)。2组治疗前后WOMAC评分比较,差异无统计学意义(P>0.05);组内比较,试验组和对照组治疗前后差异有统计学意义(均P<0.001)。试验组总有效率为80.0%(36/45),高于对照组的73.3%(33/45);试验组愈显率为33.3%(15/45),高于对照组的28.9%(13/45),2组比较差异均无统计学意义(P>0.05)。2组均未发生严重不良反应。结论局部外用化痰活血方配合电脑中频治疗与单独电脑中频治疗4周,疗效无差别;局部外用化痰活血方配合电脑中频治疗可能在缓解关节疼痛方面比单一电脑中频效果好。Objective To observe the clinical effect of eliminating phlegm and promoting blood circulation prescription on knee osteoarthritis.Methods A single-center,randomized,double-blind study was used to divide the patients into experimental group and control group.The experimental group received external Huatan Huoxui prescription combined with computer medium frequency treatment,and the control group received external placebo combined with computer medium frequency treatment.The efficacy,visual analog Scale(VAS)scores,Western Ontario and McMaster University Osteoarthritis Index(WOMAC)scores and safety of the two groups were compared.Results VAS scores before and after treatment were compared between the two groups,the difference was statistically significant(P<0.05).There was significant difference between the experimental group and the control group before and after treatment(P<0.001 for all).There was no significant difference in WOMAC scores between the two groups before and after treatment(P>0.05).There was significant difference between the experimental group and the control group before and after treatment(P<0.001 for all).The total effective rate of experimental group was 80.0%(36/45),which was higher than that of control group(73.3%,33/45).The apparent rate of experimental group was 33.3%(15/45),which was higher than that of control group(28.9%,13/45),and there was no statistical significance between the two groups(P>0.05).No serious adverse reactions occurred in the two groups.Conclusion Local and external application of eliminating phlegm and promoting blood circulation prescription combined with computerized intermediate frequency therapy may have a better effect on relieving joint pain.

关 键 词：痹证 膝骨关节炎 随机双盲法 化痰活血法 中医外治法 

分 类 号：R274.9[医药卫生—中西医结合]