多模态影像技术在高原红细胞增多症中的研究进展  

Research progress of multimodal imaging technique in high altitude polycythemia

作　　者：何鑫 张耐辉 鲍海华[1] HE Xin;ZHANG Naihui;BAO Haihua(Medical Imaging Center,Qinghai University Affifiliated Hospital,Xining 810000,China)

机构地区：[1]青海大学附属医院影像中心,西宁810000

出　　处：《磁共振成像》2023年第4期198-202,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：青海省省级临床重点专科项目(编号:青财社字[2020]1301号)。

摘　　要：高原红细胞增多症(high altitude polycythemia, HAPC)是指长期生活在海拔2500米以上的高原世居者或移居者,对高原低氧环境逐渐失去习服而导致的临床综合征,以红细胞过度增生、低氧血症为特征。由于红细胞过度增生导致血液黏稠度升高、血流阻力增加,引起一系列症状和体征,累及全身多个系统和器官。随着影像技术的不断发展,多模态影像技术对于HAPC各方面的研究作出了贡献。本文就多模态影像技术在HAPC中的研究进展进行综述,重点阐述多模态影像技术在研究HAPC的病理生理机制、评估治疗效果和预测病情进展方面的作用。High altitude polycythemia(HAPC)is a clinical syndrome caused by the gradual loss of acclimatization to the hypoxia environment at high altitude,which is characterized by excessive proliferation of red blood cells and hypoxemia.Excessive proliferation of red blood cells leads to increased blood viscosity and blood flow resistance,resulting in a series of symptoms,involving many systems and organs of the whole body.With the continuous development of imaging technology,multimodal imaging technology has contributed to the study of polycythemia at high altitude.This article reviews the research progress of multimodal imaging technology in HAPC,focusing on the role of multimodal imaging technology in studying the pathophysiological mechanism of HAPC,evaluating the treatment effect and predicting the disease progression.

关 键 词：高原红细胞增多症 计算机断层扫描 磁共振成像 基于体素的形态学分析 扩散张量成像 扩散峰度成像 血氧水平依赖功能磁共振成像 质子磁共振波谱成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R555.1[医药卫生—诊断学]