微创保胆取石术治疗胆结石患者对其术后恢复、胃肠功能的影响  

Effect of Minimally Invasive Biliary Stone Extraction on Postoperative Recovery and Gastrointestinal Function in Patients with Gallstones

作　　者：陈建宇[1,2] 陈辉[1,2] 刘志[1,2] CHEN Jianyu;CHEN Hui;LIU Zhi(Affiliated Hospital of Chuanbei Medical College,Nanchong,Sichuan Province,637000 China;Institute of Hepatobiliary,Pancreatic and Intestinal Research,Chuanbei Medical College,Nanchong,Sichuan Province,637000 China)

机构地区：[1]川北医学院附属医院,四川南充637000 [2]川北医学院肝胆胰肠研究所,四川南充637000

出　　处：《世界复合医学》2023年第1期182-185,共4页World Journal of Complex Medicine

基　　金：南充市科技项目(19SXHZ0309)。

摘　　要：目的 评估微创保胆取石术应用在胆结石患者中的效果及对其术后恢复、胃肠功能的影响。方法 纳入2020年3月—2021年9月川北医学院附属医院收治的82例胆结石患者,遵循随机数表法将患者分为两组,对照组(41例)行腹腔镜胆囊切除术,观察组(41例)行微创保胆取石术,评价比较两组胃动素、胃泌素、免疫指标、总蛋白(TP)、C反应蛋白(CRP)、消化病生存质量量表(GLQI)、围术期指标、术后并发症。结果 术前,两组胃动素、胃泌素、免疫指标、TP、CRP、GLQI对比差异无统计学意义(P>0.05);术后,观察组胃动素、胃泌素、免疫指标、TP、CRP、GLQI优于对照组,差异有统计学意义(P<0.05);较之对照组,观察组围术期指标更佳,差异有统计学意义(P<0.05),且术后观察组并发症发生率(4.88%)低于对照组(24.39%),差异有统计学意义(χ^(2)=6.248,P<0.05)。结论 对胆结石患者行微创保胆取石术,能够减轻手术创伤,减少术后并发症,促进胃肠功能、免疫功能恢复,提高生活质量。Objective To evaluate the effect of minimally invasive biliary stone extraction applied in patients with gallstones and the effect on their postoperative recovery and gastrointestinal function.Methods A total of 82 patients with gallstones admitted to Affiliated Hospital of Chuanbei Medical College from March 2020 to September 2021 were enrolled and randomly divided into two groups.The control group(41 cases)underwent laparoscopic cholecystectomy,and the observation group(41 cases)underwent minimally invasive choledocholithotomy.Motilin,gastrin,immune markers,total protein(TP),C-reactive protein(CRP),digestive disease quality of life scale(GLQI),perioperative indicators,and postoperative complications were evaluated and compared between the two groups.Results Before operation,there was no statistically significant difference in motilin,gastrin,immune index,TP,CRP and GLQI between the two groups(P>0.05).After operation,motilin,gastrin,immune index,TP,CRP and GLQI in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the perioperative indicators of the observation group were better than those in the control group,the difference was statistically significant(P<0.05),and the incidence of postoperative complications(4.88%)in the observation group was lower than that of the control group(24.39%),the difference was statistically significant(χ^(2)=6.248,P<0.05).Conclusion Minimally invasive biliary stone extraction in patients with gallstones can reduce surgical trauma,decrease postoperative complications,promote recovery of gastrointestinal function and immune function,and improve quality of life.

关 键 词：微创保胆取石术 胆结石 术后恢复 胃肠功能 

分 类 号：R656[医药卫生—外科学]