中西医结合治疗腑实热结型急性胰腺炎的临床探讨  

Clinical Discussion on the Combination of Chinese and Western Medicine in the Treatment of Acute Pancreatitis with Internal Organs and Heat Nodes

作　　者：刘继威 王骁[2] 武海娜 LIU Jiwei;WANG Xiao;WU Haina(Department of Gastroenterology,Xuzhou Mine Hospital,Xuzhou,Jiangsu Province,221000 China;Department of OncologyⅡ,Hebei Provincial Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei Province,050011 China)

机构地区：[1]徐州市矿山医院消化内科,江苏徐州221000 [2]河北省中医院肿瘤二科,河北石家庄050011

出　　处：《系统医学》2023年第1期54-57,共4页Systems Medicine

基　　金：河北省中医药管理局科研计划项目(2020054)。

摘　　要：目的分析腑实热结型急性胰腺炎西医与中西医结合治疗的疗效差异。方法选取2017年10月—2021年10月徐州市矿山医院和河北省中医院住院的60例腑实热结型急性胰腺胰腺炎患者为研究对象,采用随机数表法分为对照组和研究组,各30例。对照组采用常规西医治疗,研究组在西医治疗基础上联合中药口服。对比两组患者治疗前后的血清淀粉酶(AMS)、白细胞(WBC)、C反应蛋白(CRP)、降钙素原(PCT)水平的变化以及临床疗效。结果研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。治疗后,两组的AMS水平较治疗前降低,差异有统计学意义(P<0.05),研究组AMS水平对照组更低,但差异无统计学意义(P>0.05)。治疗后,两组WBC、CRP、PCT的水平均显著降低,且研究组WBC(6.54±1.69)×109/L、CRP(46.77±35.61)mg/L、PCT(0.27±0.29)ng/mL低于对照组,差异有统计学意义(t=4.506、3.131、3.268,P<0.05)。结论中西医结合治疗在改善急性胰腺炎患者的炎症因子水平及临床疗效优于单纯使用西药治疗,可以加快胰腺炎患者的康复,值得临床借鉴与应用。Objective To analysed the difference in efficacy between Western medicine and combined Chinese and Western medicine in the treatment of acute pancreatitis with internal organs and heat knots.Methods 60 patients of Fu Shi hot junction type acute pancreatic pancreatitis admitted to Xuzhou Mine Hospital and Hebei Provincial Hospital of Traditional Chinese Medicine from October 2017 to October 2021 were selected as the study subjects and divided into control group and study group by the random number table method,with 30 cases each.The control group was treated with conventional western medicine,and the study group was treated on the basis of Western medicine combined with traditional Chinese medicine orally.Serum amylase(AMS),white blood cell(WBC),C-reactive protein(CRP),procalcitonin(PCT)levels before and after treatment and clinical outcomes were compared between the two groups.Results The clinical efficacy of the study group was better than that of the control group,the difference was statistically significant(P<0.05).After treatment,the AMS level of the two groups decreased compared with before treatment,the difference was statistically significant(P<0.05),and the study group was lower than the control group,but the difference was not statistically significant(P>0.05).After treatment,the levels of WBC,CRP,and PCT were significantly reduced of the two groups,and WBC(6.54±1.69)×10^(9)/L,CRP(46.77±35.61)mg/L,PCT(0.27±0.29)ng/mL in the study group were lower than the control group,the difference was statistically significant(t=4.506,3.131,3.268,P<0.05).Conclusion Combined Chinese and Western medicine treatment is better than the use of Western medicine alone in improving the level of inflammatory factors and clinical efficacy in patients with acute pancreatitis,and can accelerate the recovery of patients with pancreatitis,which is worthy of clinical reference and application.

关 键 词：急性胰腺炎 中西医结合治疗 临床研究 疗效 

分 类 号：R4[医药卫生—临床医学]