益气养营汤在人工膝关节置换围手术期临床疗效  

The study of effect of YiqiYangying Decoction used in perioperation for cases of severe knee osteoarthritis treated by artificial knee resurfacing surgery

作　　者：李亮[1] 周正新[1] 李文华[1] 刘涛 朱磊[1] 康金平[1] LI Liang;ZHOU Zhengxin;LI Wenhua;LIU Tao;ZHU Lei;KANG Jinping(The Second Department of Orthopedics,the First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,China)

机构地区：[1]安徽中医药大学第一附属医院骨二科,合肥230031

出　　处：《实用医学杂志》2023年第7期904-909,共6页The Journal of Practical Medicine

基　　金：安徽省自然科学基金项目(编号:2008085MH281)。

摘　　要：目的观察益气养营汤在重度膝骨关节炎人工膝关节表面置换围手术期应用临床疗效。方法将82例重度膝骨关节炎住院患者随机分为对照组与观察组,每组41例,对照组采用微创板式器械人工膝关节表面置换手术+常规ERAS,观察组在对照组治疗基础上,于术后第2天应用益气养营汤水煎剂内服一日一剂,分两次服用,连续1周,比较两组手术前、术后第1天以及术后第8天的血常规红细胞(RBC)和血红蛋白(HGB)以及D-二聚体数值,手术前以及术后第8天的膝关节活动度、膝关节VAS评分、骨关节炎的严重程度指数和中医病证临床疗效。结果两组RBC和HGB术后第1天较术前显著下降,两组RBC和HGB术后第8天较术后第1天均显著上升,且观察组RBC和HGB显著高于对照组。两组D-二聚体术后第1天较术前显著升高,两组D-二聚体术后第8天较术后第1天均显著降低,且观察组D-二聚体降低幅度显著优于对照组。两组膝关节活动度术后第8天较术前均显著改善,且观察组优于对照组。两组VAS评分、骨关节炎的严重程度指数术后第8天较术前均显著下降,且观察组优于对照组。观察组痊愈26例,显效12例,愈显率92.7%,对照组痊愈20例,显效13例,愈显率80.5%,观察组愈显率显著高于对照组。结论重度膝骨关节炎人工膝关节表面置换围手术期应用益气养营汤可改善术后贫血及凝血功能,缓解疼痛,改善关节活动功能,提高中医病证疗效,加速患者术后康复。Objective To study clinical curative effect of YiqiYangying Decoction used in perioperation for cases of severe knee osteoarthritis treated by artificial knee resurfacing surgery.Methods According to the in⁃clusion and exclusion criteria,82 patients with severe knee osteoarthritis were randomly assigned to one of two groups:the control group and the YiqiYangying Decoction observation group.Patients in the control group under⁃went artificial knee resurfacing surgery with conventional enhanced recovery after surgery.In the observation group,patients were given YiqiYangying Decoction for seven days in addition to the above⁃mentioned treatment.To take statistical analysis of RBC,HGB,D⁃dimer of the patients in the two groups before,one day and eight days after the surgery.To compare knee range of motion,VAS and Lequesne MG of the patients in the two groups before and eight days after the surgery.Results RBC and HGB levels in both groups were significantly lower one day after surgery than before.RBC and HGB levels in both groups were significantly lower one day after surgery than before.RBC and HGB levels in the two groups were significantly higher eight days after surgery than one day after surgery.The RBC and HGB of the observation group were significantly higher than those of the control group.D⁃dimer of the two groups one day after the surgery was significantly higher than before surgery and D⁃dimer of the two groups eight days after the surgery was significantly lower than one day after the surgery.D⁃dimer of the the observation group was significantly lower than the control group.Knee range of motion of the two groups eight days after the surgery was significantly higher than before operation.Knee range of motion of the observation group was significantly higher than the control group.VAS and Lequesne MG of the two groups eight days after the surgery was significantly lower than before operation.VAS and Lequesne MG of the observation group was significantly lower than the control group.Twenty⁃six

关 键 词：膝骨关节炎 益气养营汤 人工膝关节表面置换手术 加速康复外科 静脉血栓栓塞症 

分 类 号：R274.9[医药卫生—中西医结合]