妊娠期糖尿病不同转归结局患者FPG、HbAlc指标水平差异性研究  

Study on the Difference of Fpg and Hbalc in Patients with Diabetes During Pregnancy with Different Outcomes

作　　者：张怡舜 颜涛玲 吴松龄 ZHANG Yishun;YAN Taoling;WU Songling(Department of Obstetrics and Gynecology,the Second Affiliated Hospital of Xiamen Medical College,Xiamen,Fujian Province,361021 China;Department of Breast Surgery,the Second Affiliated Hospital of Xiamen Medical College,Xiamen,Fujian Province,361021 China)

机构地区：[1]厦门医学院附属第二医院妇产科,福建厦门361021 [2]厦门医学院附属第二医院乳腺外科,福建厦门361021

出　　处：《糖尿病新世界》2023年第1期41-45,共5页Diabetes New World Magazine

摘　　要：目的探究妊娠糖尿病不同转归结局患者FPG、HbAlc指标水平的差异性。方法选取2019年1月—2021年12月厦门医学院附属第二医院收治的1000例GDM产妇作为研究对象,根据妊娠期糖尿病转归结局分为正常糖耐量组(NGT组)879例、葡萄糖耐量异常组(IGT组)52例、空腹血糖调节受损组(IFG组)47例及2型糖尿病组(T2DM)22例。对比4组孕期6周到产后6周的FPG、HbA1c指标变化。结果与NGT组相比,IGT组、IFG组、T2DM组FPG、HbA1c指标水平较高,差异有统计学意义(P<0.05);与NGT组相比,IGT组、IFG组、T2DM组FPG、HbA1c指标异常状态持续时间较长,差异有统计学意义(P<0.05);NGT组相比,IGT组、IFG组、T2DM组FPG、HbA1c指标异常状态时间占总妊娠时间比重较大,差异有统计学意义(P<0.05)。结论妊娠糖尿病不同转归结局患者FPG、HbAlc指标水平存在显著差异性,为妊娠糖尿病不良转归结局的预测提供研究方向。Objective To explore the difference of FPG and HbAlc in patients with pregnancy diabetes with different outcomes.Methods A total of 1000 pregnant women with GDM admitted to the Second Affiliated Hospital of Xiamen Medical College from January 2019 to December 2021 were selected as research subjects.According to the outcome of diabetes in pregnancy,they were divided into 879 cases of normal glucose tolerance group(NGT group),52 cases of abnormal glucose tolerance group(IGT group),47 cases of impaired fasting glucose regulation group(IFG group)and 22 cases of type 2 diabetes group(T2DM group).Compared the changes of FPG and HbA1c in the four groups from 6 weeks gestation to 6 weeks postpartum.Results Compared with NGT group,the levels of FPG and HbA1c in IGT group,IFG group and T2DM group were higher,and the difference was statistically significant(P<0.05).Compared with NGT group,the abnormal state of FPG and HbA1c in IGT group,IFG group and T2DM group lasted longer,and the difference was statistically significant(P<0.05).Compared with NGT group,the abnormal state time of FPG and HbA1c indexes in IGT group,IFG group and T2DM group accounted for a large proportion of the total pregnancy time,and the difference was statistically significant(P<0.05).Conclusion There are significant differences in FPG and HbAlc levels in patients with different outcomes of gestational diabetes,which provides research direction for predicting the adverse outcomes of gestational diabetes.

关 键 词：妊娠期糖尿病 血糖 糖化血红蛋白 动态监测 疾病转归 

分 类 号：R587.1[医药卫生—内分泌]