猴痘病毒进化及检测技术研究进展  

Research progress in evolution and detection technology of monkeypox virus

作　　者：祁贤[1] QI Xian(Jiangsu Provincial Center for Disease Control and Prevention,Jiangsu Nanjing 210009,China)

机构地区：[1]江苏省疾病预防控制中心,江苏南京210009

出　　处：《江苏预防医学》2023年第1期1-7,共7页Jiangsu Journal of Preventive Medicine

基　　金：国家自然科学基金猴痘相关重要基础科学问题研究专项项目(82241067);江苏省自然科学基金面上项目(BK20191489);江苏省自然科学基金面上项目(BK20221413)。

摘　　要：猴痘病毒是与天花病毒近亲的一种正痘病毒。2022年,猴痘病毒在全球100多个国家引起暴发和流行,成为年度国际关注的突发公共卫生事件。与之前的暴发疫情相比,引发2022年疫情的猴痘病毒明显增强了对人体的适应性,传播范围持续扩大,导致全球大流行的风险增加。现对猴痘病毒分子进化及实验室检测技术的最新进展进行综述,并对猴痘病毒未来的研究方向和防控策略提出思考和建议。Monkeypox virus belongs to the orthopoxvirus,which islosely related to smallpox virus.In 2022,outbreak and epidemic caused by monkeypox virus occurred in more than 100 countries around the world,which was declared as a global health emergency.Compared with the previous outbreaks,the monkeypox virus that caused the epidemic in 2022 has significantly enhanced its adaptability to human,and its spread continues to expand,and the risk of causing a new pandemic is increasing.In this review,we discussed the lat-est progress of molecular evolution and laboratory detection technology of monkeypox virus,and made some thoughts and suggestions on the future research and prevention and control of monkeypox virus.

关 键 词：猴痘病毒 IIb-B1谱系 病毒进化 检测技术 

分 类 号：R373.1[医药卫生—病原生物学]