儿童支原体合并乙型流行性感冒病毒感染的影响因素分析  

Analysis of influencing factors of Mycoplasma combined with influenza B virus infection in children

作　　者：杨政 钱雪莹 沈志英 庾玉婷 万荣 YANG Zheng;QIAN Xueying;SHEN Zhiying;YU Yuting;WAN Rong(Department of Pediatrics,Jiangsu Shengze Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Suzhou215228,China;Department of Medical Record Statistics,Jiangsu Shengze Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Suzhou215228,China)

机构地区：[1]南京医科大学附属江苏盛泽医院儿科,江苏苏州215228 [2]南京医科大学附属江苏盛泽医院病案统计科,江苏苏州215228

出　　处：《中国医药导报》2023年第11期102-105,共4页China Medical Herald

基　　金：江苏省妇幼健康科研项目(F201858)。

摘　　要：目的分析儿童支原体合并乙型流行性感冒病毒(IFVB)感染的影响因素。方法选取2018年4月至2022年3月南京医科大学附属江苏盛泽医院肺炎支原体(MP)感染的支气管肺炎患儿248例,根据是否合并IFVB感染分为MP组、MP合并IFVB组。比较两组临床特征、细胞免疫指标、体液免疫指标,并分析病情转归情况;分析MP合并IFVB的影响因素。结果121例患儿MP合并IFVB。MP合并IFVB组咳嗽、咳痰、斑片状影、肺实变、湿啰音占比,中性粒细胞计数,单核细胞,CD^(8+),IgG,IgA,IgM高于MP组;肺纹理正常占比、淋巴细胞计数、CD^(3+)、CD^(4+)低于MP组;发热时间、咳嗽好转时间、湿啰音消失时间、住院时间长于MP组(P<0.05)。CD^(3+)、CD^(4+)、CD^(8+)、IgG、IgA、IgM为MP合并IFVB感染的影响因素(P<0.05)。结论儿童MP合并IFVB感染的临床特征明显,CD^(3+)、CD^(4+)、CD^(8+)、IgG、IgA、IgM均为其重要影响因素。Objective To study the influencing factors of Mycoplasma combined with influenza B virus(IFVB)infection in children.Methods Two hundred and forty-eight children with bronchopneumonia infected by Mycoplasma pneumoniae(MP)in Jiangsu Shengze Hospital Affiliated to Nanjing Medical University from April 2018 to March 2022 were selected.They were divided into MP group and MP merge IFVB group.The clinical characteristics,cellular immunity,and humoral immunity were compared between two groups,and the prognosis of the disease was analyzed;the influencing factors of MP combined with IFVB were analyzed.Results A total of 121 children with MP combined with IFVB.The proportion of cough,sputum,patchy shadow,lung compunction,wet rale,and neutrophil count,monocyte,CD^(8+),IgG,IgA,and IgM in MP merge IFVB group was higher than that in MP group;the proportion of normal lung texture,and lymphocyte count,CD^(3+),and CD^(4+)was lower than that in MP group,and fever time,cough improvement time,wet rales disappearance time,and hospitalization time were longer than those in MP group(P<0.05).CD^(3+),CD^(4+),CD^(8+),IgG,IgA,and IgM were the influencing factors of MP combined with IFVB infection(P<0.05).Conclusion The clinical characteristics of MP combined with IFVB infection in children are obvious,and CD^(3+),CD^(4+),CD^(8+),IgG,IgA,and IgM are all important influencing factors.

关 键 词：支原体 乙型流行性感冒病毒 影响因素 免疫功能 

分 类 号：R563.1[医药卫生—呼吸系统]