The application of intraoperative neurophysiological monitoring in selective dorsal neurotomy for primary premature ejaculation:a prospective single-center study  

作　　者：Qing-Lai Tang Tao Song You-Feng Han Bai-Bing Yang Jian-Huai Chen Zhi-Peng Xu Chun-Lu Xu Yang Xu Wen Yu Wei Qiu Jiong Shi En-Si Zhang Yu-Tian Dai 

机构地区：[1]Department of Andrology,Drum Tower Clinical Medical College,Nanjing Medical University,Nanjing 210008,China [2]Department of Urology,The Affiliated Jiangning Hospital of Nanjing Medical University,Nanjing 211100,China [3]Department of Pathology,The Affiliated Jiangning Hospital of Nanjing Medical University,Nanjing 211100,China [4]Department of Pathology,Drum Tower Clinical Medical College,Nanjing Medical University,Nanjing 210008,China

出　　处：《Asian Journal of Andrology》2023年第1期137-142,共6页亚洲男性学杂志（英文版）

基　　金：supported by Jiangsu provincial key R&D plan special fund (Social Development)project in China (No.BE2019606).

摘　　要：Selective dorsal neurotomy(SDN)is a surgical treatment for primary premature ejaculation(PE),but there is still no standard surgical procedure for selecting the branches of the dorsal penile nerves to be removed.We performed this study to explore the value of intraoperative neurophysiological monitoring(IONM)of the penile sensory-evoked potential(PSEP)for standard surgical procedures in SDN.One hundred and twenty primary PE patients undergoing SDN were selected as the PE group and 120 non-PE patients were selected as the normal group.The PSEP was monitored and compared between the two groups under both natural and general anesthesia(GA)states.In addition,patients in the PE group were randomly divided into the IONM group and the non-IONM group.During SDN surgery,PSEP parameters of the IONM group were recorded and analyzed.The differences in PE-related outcome measurements between the perioperative period and 3 months'postoperation were compared for the PE patients,and the differences in effectiveness and complications between the IONM group and the non-IONM group were compared.The results showed that the average latency of the PSEP in the PE group was shorter than that in the normal group under both natural and GA states(P<0.001).Three months after surgery,the significant effective rates in the IONM and non-IONM groups were 63.6%and 34.0%,respectively(P<0.01),and the difference in complications between the two groups was significant(P<0.05).IONM might be useful in improving the short-term therapeutic effectiveness and reducing the complications of SDN.

关 键 词：intraoperative neurophysiological monitoring primary premature ejaculation selective dorsal neurotomy 

分 类 号：R697[医药卫生—泌尿科学]