基于人体呼气检测应用的气体传感器  

Gas⁃Sensing Technology for Human Breath Detection

作　　者：赵京龙 沈文锋[2,3] 吕大伍 尹嘉琦 梁彤祥 宋伟杰 Jinglong Zhao;Wenfeng Shen;Dawu Lv;Jiaqi Yin;Tongxiang Liang;Weijie Song(Department of Materials Metallurgy and Chemistry,Jiangxi University of Science and Technology,Ganzhou 341099,China;Ningbo Institute of Materials Technology and Engineering,Chinese Academy of Sciences,Ningbo 315201,China;University of Chinese Academy of Sciences,Beijing 100049,China;School of Materials Science and Engineering,Shanghai University,Shanghai 200044,China)

机构地区：[1]江西理工大学材料冶金化学学部,赣州341099 [2]中国科学院宁波材料技术与工程研究所,宁波315201 [3]中国科学院大学,北京100049 [4]上海大学材料科学与工程学院,上海200044

出　　处：《化学进展》2023年第2期302-317,共16页Progress in Chemistry

基　　金：浙江省自然科学基金项目(LGF22F010008);宁波市自然科学基金项目(No.202003N4362,202003N4332)资助。

摘　　要：人体呼气中挥发性有机物浓度的变化与某些疾病密切相关,通过分析人体呼气中的挥发性有机物来诊断疾病是一种无创非侵入性、操作方便的手段,近年来在疾病诊断和早期筛查方面的应用中受到越来越多的关注。目前检测呼气中挥发性有机物的设备主要有两类:质谱类分析仪器和气敏传感器。气敏传感器具有易集成、小型化、成本低、操作简单等优势,在未来大规模人群疾病的诊断和早期筛查中具有广阔的应用前景。本综述系统地阐述了气敏传感器的工作机制、传感器性能、不同敏感材料的应用现状和不同的气体传感器类型在人体呼气检测中的应用情况,同时介绍了与部分疾病存在关联的人体呼气中挥发性有机物的种类,之后对呼气采样手段和目前常用的数据处理方法也进行了简单介绍。最后指出了目前气体传感器技术在呼气检测方面存在的问题,并展望了气体传感器技术在人体呼气检测中的未来发展前景。Changes in volatile organic compounds concentrations in human breath are closely related to certain diseases,and the diagnosis of diseases by analyzing volatile organic compounds in human breath is a non⁃invasive,and easy⁃to⁃use tool that has received increasing attention in recent years for applications in disease diagnosis and early screening.There are currently two main types of equipment for detecting volatile organic compounds in exhaled breath:mass spectrometry⁃based analytical instruments and gas⁃sensitive sensors.With easy integration,miniaturization,low cost,and simple operation,gas⁃sensitive sensors have broad application prospects in the future diagnosis and early screening of large⁃scale population diseases.This review systematically describes the working mechanism of gas sensors,sensor performance,the current status of application of different sensitive materials and the application of different gas sensor types in human breath detection,the types of volatile organic compounds in human breath that are associated with some diseases are also introduced,which is followed by a brief introduction to the means of breath sampling and the data processing methods currently in use.Finally,the problems of current gas sensor technology in breath detection are pointed out,and the prospects of gas sensor technology in human breath detection are foreseen.

关 键 词：呼气分析 气体传感器挥发性有机物非侵入性诊断 

分 类 号：O649[理学—物理化学] N39[理学—化学]