牛膝活血汤联合早期许氏伤药外敷治疗气滞血瘀证踝关节骨折对患者关节肿痛的影响  

Effect of Niuxi Huoxue Decoction Combined with Early XU’s Injury Medicine on Joint Swelling and Pain for Patients with Ankle Joint Fracture of Qi Stagnation and Blood Stasis Syndrome

作　　者：冯志[1] 范斌[1] FENG Zhi;FAN Bin(The Third People's Hospital of Mianyang City,Mianyang Sichuan 621000,China)

机构地区：[1]绵阳市第三人民医院,四川绵阳621000

出　　处：《四川中医》2023年第1期152-156,共5页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:观察牛膝活血汤联合早期许氏伤药外敷治疗气滞血瘀证踝关节骨折对患者关节肿痛的影响。方法:选取我院于2018年10月~2020年10月收治的中医辨证为气滞血瘀证的踝关节骨折术后肿胀患者80例,参照其治疗方案进行均分组。所有均给予手术治疗,术后给予复方甘露醇注射液/甘油果糖注射液等常规治疗,对照组40例加用早期许氏伤药外敷治疗,观察组40例加用牛膝活血汤联合早期许氏伤药外敷治疗。统计两组优良率、并发症率,检测两组炎症因子的表达,记录踝关节的周长、视觉模拟评分(VAS)评分、踝关节功能Kofoed评分、中医证候积分的差别。结果观察组优良率高于对照组,有统计学意义(P<0.05)。治疗4周后两组C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)等均大幅下降(P<0.05),且观察组治疗4周后CRP、TNF-α较对照组更低(P<0.05)。术后4周、术后8周两组踝关节的周长、VAS评分、中医证候积分等均大幅下降(P<0.05),踝关节功能Kofoed评分大幅提升(P<0.05),且观察组术后4周踝关节的周长较对照组更低(P<0.05),术后8周踝关节的周长与对照组相似(P>0.05),观察组术后4周、术后8周VAS评分、中医证候积分较对照组更低(P<0.05),踝关节功能Kofoed评分较对照组更高(P<0.05)。观察组并发症发生率与对照组比较,无统计学意义(P>0.05)。结论:牛膝活血汤联合早期许氏伤药外敷治疗气滞血瘀证踝关节骨折可有缓解关节肿胀和疼痛,抑制炎症反应,促进术后康复,提高疗效。Objective:The effect of Nixie Huoxue Decoction combined with early external application of XU’s injury medicine to treat ankle fracture with Qi stagnation and blood stasis syndrome for patients with joint swelling and pain.Methods:From October 2,018 to October 2,020,80 patients with swelling after ankle fracture with Qi stagnation and blood stasis syndrome were selected.All of them were treated by operation,compound mannitol injection/glycerol fructose injection was given after operation,40 cases in the controlled group were treated with early XU’s wound medicine,40 cases in the observation group were treated with Huangqi Huoxue Decoction combined with early XU’s wound medicine.The excellent and good rate and complication rate of the two groups were counted,and the expression of inflammatory factors in the two groups was detected.The circumference of ankle joint,visual simulation score(VAS)score,ankle function Kofoed score,TCM syndrome score were recorded.Results:Excellent and good rate in the observation group was higher than that in the controlled group(P<0.05).The C reactive protein(CRP)and tumor necrosis factor-α(TNF-α)decreased significantly(P<0.05)after 4 weeks of treatment,and the CRP,TNF-αin the observation group was lower than that in the controlled group(P<0.05).The ankle circumference,VAS score and TCM syndrome score of the two groups decreased significantly(P<0.05),the ankle function Kofoed score increased significantly(P<0.05).After 8 weeks,the circumference of ankle joint was similar to that of the controlled group(P>0.05).The scores of VAS and TCM syndromes in the observation group were lower than those in the controlled group(P<0.05),and the score of ankle function Kofoed was higher than that in the controlled group(P<0.05).Compared with the controlled group,the incidence of complications in the observation group was not statistically significant(P>0.05).Conclusion:Huangqi Huoxue Decoction combined with early XU’s injury medicine external application in the treatment of ankle joint frac

关 键 词：牛膝活血汤 早期许氏伤药外敷 气滞血瘀证 踝关节骨折 关节肿痛 

分 类 号：R683[医药卫生—骨科学]