下肢深静脉瓣膜替代物的发展现状  

Progress of deep venous valve substitutes of lower extremity

作　　者：郑葳 吴英锋[1,2] Zheng Wei;Wu Yingfeng(Department of Vascular Surgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Department of Vascular Surgery,Beijing Luhe Hospital,Capital Medical University,Beijing 101199,China)

机构地区：[1]首都医科大学宣武医院血管外科,北京100053 [2]首都医科大学附属北京潞河医院血管外科,北京101199

出　　处：《血管与腔内血管外科杂志》2023年第3期338-344,共7页Journal of Vascular and Endovascular Surgery

摘　　要：深静脉瓣膜功能不全导致反流是下肢慢性静脉疾病的重要原因。技术难度、患者个体情况等原因限制了开放手术直接纠正瓣膜功能的应用,静脉瓣膜的置换成了更有潜力的治疗方式。目前,天然材料、合成材料、组织工程瓣膜各有其利弊,在瓣膜制作的发展过程中展示了多种可能性,尤其是组织工程为瓣膜制造提供了新途径。本文通过总结国内外瓣膜替代物的相关文献,对下肢深静脉瓣膜替代物进行综述,以期促进下肢慢性静脉疾病治疗的发展。Deep venous valve insufficiency is an important cause of chronic venous disease of lower extremity.Technical difficulties and individual conditions limit the application of open surgery to directly correct the valve function,and venous valve replacement has become a more promising treatment method.The natural,synthetic and tissue-engineered valves currently explored have their own advantages and disadvantages,demonstrating a variety of possibilities on the process of valve construction.Tissue engineering in particular offers new method.Through a review of the literatures about venous valve substitutes published in China and abroad,this study is aimed to summarize the progress of deep venous valve substitutes of lower extremity to promote the development of the treatment of chronic venous disease.

关 键 词：慢性静脉功能不全 人工静脉瓣膜 

分 类 号：R543[医药卫生—心血管疾病]