藏药佐摸兴的本草考证及用药调查  

Herbal Literature Research and Drug Use Investigation of Tibetan Medicine Zuomoxing

作　　者：袁茂华[1,2] 高必兴 陶静 古锐 蒋桂华[1] YUAN Mao-hua;GAO Bi-xing;TAO Jing;GU Rui;JIANG Gui-hua(State Key Laboratory of Southwestern Chinese Medicine Resources,School of Pharmacy,Chengdu University of TCM,Chengdu 611137,China;Leshan Food and Drug Inspection and Testing Center,The Key Laboratory of Traditional Chinese Medicine Quality Control of Sichuan Provincial Drug Administration,Leshan 614000,China;Sichuan Institute for Drug Control/Key Laboratory of Quality Evaluation of Chinese Patent Medicines,NMPA,Chengdu 611731,China)

机构地区：[1]成都中医药大学药学院,西南特色中药资源国家重点实验室,四川成都611137 [2]乐山市食品药品检验检测中心,四川省药品监督管理局中药质量控制重点实验室,四川乐山614000 [3]四川省药品检验研究院/国家药品监督管理局中成药质量评价重点实验室,四川成都611731

出　　处：《南京中医药大学学报》2023年第4期375-383,共9页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家重点研发计划项目(2019YFC1712302,2019YFC1712305);国家自然科学基金面上项目(82173928)。

摘　　要：目的厘清藏药佐摸兴的基原、药用部位、临床及市场流通使用情况,为其进一步研究和开发提供参考。方法采用本草文献考证针对佐摸兴基原、药用部位及制剂等进行梳理;对四川、青海、西藏、云南4省区、41个市县、21家藏医院、13个制药厂及药材公司、6位藏医药专家进行了基原及药用情况调查,并结合所收集的药材鉴定结果推导出相应基原使用情况。结果文献考证显示佐摸兴涉及10个基原,药用木质部心材、煎膏、叶、花等。调研结果显示最广泛认可的佐摸兴基原为昌都锦鸡儿Caragana changduensis Y.X.Liou,其次是鬼箭锦鸡儿C.jubata(Pall.)Poir.,主要以昌都锦鸡儿红色心材入药,质量最佳,其他颜色鬼箭锦鸡儿心材使用较少,效果稍差。市场上流通佐摸兴药材以昌都锦鸡儿为主,少数藏医院使用鬼箭锦鸡儿。文献考证和调查总计涉及成方制剂20个,佐摸兴在制剂中常用的功效主要为降压、清血热、化血瘀,并可治疗多血症。结论明确了藏药佐摸兴药材的主要来源为昌都锦鸡儿的红色心材,可为其进一步开发利用提供依据。OBJECTIVE To clarify the origins,medicinal parts,clinical use and market circulation of Tibetan medicine Zuomoxin,and provide a reference for its further research and development.METHODS The origins,medicinal parts,and preparations of Zuomoxing were sorted out by adopting TCM literature research;the usage of corresponding origins was derived based on the origin and medicinal condition survey that was conducted with 41 cities and counties,21 Tibetan hospitals,13 pharmaceutical factories and pharmaceutical companies,and 6 Tibetan medical experts in the four provinces and regions of Sichuan,Yunnan,Tibet,and Qinghai,as well as the identification results of collected medicinal materials.RESULTS Literature research showed that Zuomoxing involved 10 origins,such as xylem heartwood,decoction,leaves,flowers,etc.The survey results suggested that the most widely recognized origin of Zuomoxing was C.changduensis Y.X.Liou,and the second was C.jubata(Pall.)Poir.The red heartwood of C.changduensis Y.X.Liou was primarily used as medicine,with the best quality.The heartwood of C.jubata(Pall.)Poir of other colors was less used and has poor effects.On the market,the most popular medicinal material for Zuomoxing was C.changduensis Y.X.Liou,and a few Tibetan hospitals use C.jubata(Pall.)Poir.This study involved a total of 20 prescription preparations.The commonly used therapeutic effects of Zuomoxing in preparations were mainly to reduce blood pressure,treat polyemia,clear blood heat,and dissipate blood stasis.CONCLUSION This study confirmed that the main source of Tibetan medicine Zuomoxing is the red heartwood of C.changduensis Y.X.Liou,which provides a basis for its further development and utilization.

关 键 词：藏药 佐摸兴 昌都锦鸡儿 鬼箭锦鸡儿 药用现状 

分 类 号：R281.4[医药卫生—中药学]