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作 者:许素墩[1] 赵婷鹭[1] 兰恩西[1] XU Sudun;ZHAO Tinglu;LAN Enxi(The First Affiliated Hospital of Xiamen University,Xiamen,Fujian,361003,China)
出 处:《中西医结合护理(中英文)》2023年第2期9-12,共4页Journal of Clinical Nursing in Practice
摘 要:目的探讨针对性心理护理结合健康教育在晚期肝癌患者术后康复中的应用效果。方法以2018年10月至2021年10月厦门大学附属第一医院收治的100例晚期肝癌患者为研究对象,采用随机数字表法将其分为2组,对照组(50例)给予健康教育护理,观察组(50例)给予针对性心理护理结合健康教育护理。比较2组的血清肿瘤标志物和免疫功能指标水平,以及抑郁自评量表(SDS)、焦虑自评量表(SAS)评分。结果护理7 d及14 d后,2组的血清甲胎蛋白、甲胎蛋白异质体-L3、癌胚抗原及糖类抗原19-9水平均低于同组护理前(P均<0.05),外周血T淋巴细胞亚群(CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+))及自然杀伤细胞水平均高于同组护理前(P均<0.05),且观察组的上述指标水平均优于同期对照组(P均<0.05)。与同组护理前比较,2组在护理7 d及14 d后的SDS、SAS评分均降低(P均<0.05),且观察组的评分均较同期对照组更低(P均<0.05)。结论针对性心理护理结合健康教育可降低晚期肝癌患者的肿瘤标志物水平,增强其免疫功能,改善其心理状态。Objective To explore the application effect of targeted psychological nursing combined with health education on the postoperative rehabilitation of patients with advanced liver cancer.Methods A total of 100 advanced liver cancer patients admitted to the First Affiliated Hospital of Xiamen University from October 2018 to October 2021 were selected as the study subjects.They were divided into two groups by random number table method.The control group(50 cases)was given nursing of health education,and the observation group(50 cases)was given targeted psychological nursing combined with nursing of health education.The levels of serum tumor markers and immune function indicators,as well as the scores of Self-Rating Depression Scale(SDS)and Self-Rating Anxiety Scale(SAS)were compared between the two groups.Results After 7 and 14 days of nursing,the levels of serum alpha-fetoprotein,alpha-fetoprotein heterologous-L3,carcinoembryonic antigen,and carbohydrate antigen 19-9 in the two groups were lower than those before nursing(all P<0.05),and the levels of peripheral blood T lymphocyte subsets(CD3^(+),CD4^(+),CD4^(+)/CD8^(+))and natural killer cells were higher than those before nursing(all P<0.05).The levels of the above indicators in the observation group were better than those in the control group on the corresponding period(all P<0.05).Compared with those before nursing,the SDS and SAS scores of the two groups decreased after 7 and 14 days of nursing(all P<0.05).The scores in the observation group were lower than those in the control group(all P<0.05).Conclusion Targeted psychological nursing combined with health education can reduce the levels of tumor markers in patients with advanced liver cancer,enhance their immune function,and improve their psychological status.
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