火针围刺联合夹脊电针治疗急性期带状疱疹:随机对照试验  

Acute herpes zoster treated with surrounding fire needling combined with electroacupuncture at Jiājĭ (夹脊EX-B2): A randomized controlled trial

作　　者：逄静 尹洪娜[1] 孙忠人[2] 夏昆鹏[1] Jing PANG;Hong-Na YIN;Zhong-Ren SUN;Kun-Peng XIA(Second Affiliated Hospital,Heilongjiang University of Chinese Medicine,Harbin 150001,China;Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学附属第二医院,哈尔滨150001 [2]黑龙江中医药大学,哈尔滨150040

出　　处：《World Journal of Acupuncture-Moxibustion》2023年第2期111-117,共7页世界针灸杂志（英文版）

基　　金：Supported by TCM Evidence-based Capacity Building Project of State Administration of Traditional Chinese Medicine:2019XZZX-ZJ005。

摘　　要：ObjectivesTo investigate the clinical efficacy of surrounding fire needling combined with electroacupuncture (EA) at Jiājĭ (夹脊EX-B2) on acute herpes zoster, and explore the potential mechanism of this combined treatment by measuring the changes of serum inflammatory cytokines and pain mediators.MethodsSixty patients with acute herpes zoster were randomly assigned to either acupuncture plus western medicine group or western medicine group. In the western medicine group, the patients took orally mecobalamin and ganciclovir for 14 consecutive days. In the acupuncture plus western medicine group, on the base of the western medicine, the surrounding fire needling (fire needling was operated swiftly toward the center of skin lesions.) combined with EA at EX-B2 was provided. Acupoints of EX-B2 were selected based on the nerve ganglion corresponding to the skin lesions, as well as two adjacent nerve ganglions(one level upwards and one downwards) to the lesions, and were stimulated with EA once daily for 14 days. The change of symptoms from the blister eruption to scabbing and decrustation were observed. The score of visual analogue scale (VAS), serum inflammatory cytokines (interleukin-1β, interleukin-6, tumor necrosis factor-α) and pain mediators (calcitonin gene related peptide, substance P) before and after treatment, the scores of Pittsburgh sleep quality index (PSQI) and Hamilton depression scale (HAMD) before and after treatment as well as at 1 month of follow-up, and the overall effective rate and the incidence of post-hepatic neuralgia at 1 month of follow-up were assessed and compared between two groups, respectively.ResultsAfter treatment completion, the time of blister relief, scabbing and decrustation in the acupuncture plus western medicine group was significantly shorter when compared with that of the western medicine group (all P < 0.05). After treatment, VAS score, PSQI score and HAMD score were all reduced significantly when compared with that before treatment within group (P < 0.05). These score

关 键 词：Herpes Zoster Randomized controlled trial(RCT) Surrounding fire needling Electroacupuncture at Jiaji(夹脊EX-B2) ANALGESIA 

分 类 号：R246.7[医药卫生—针灸推拿学]