经主动脉内球囊反搏对急性重症心肌炎的疗效及心肾功能的改善价值  

Effect of Intra-aortic Balloon Pump on Acute Severe Myocarditis and Its Value in Improving Cardiac and Renal Function

作　　者：庾海清[1] 杨春万[1] 莫月媚[1] YU Haiqing;YANG Chunwan;MO Yuemei(不详;The First People's Hospital of Zhaoqing City,Zhaoqing 526020,China)

机构地区：[1]肇庆市第一人民医院,广东肇庆526020

出　　处：《中外医学研究》2023年第10期1-6,共6页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：肇庆市科技创新指导类项目(190408094161537)。

摘　　要：目的:探讨经主动脉内球囊反搏(IABP)对急性重症心肌炎的疗效及心肾功能的改善价值。方法:将肇庆市第一人民医院2019年1月—2021年12月收治的60例急性重症心肌炎患者纳入研究,根据随机数表法分为观察组和对照组,各30例。对照组给予常规治疗,观察组在对照组基础上联用IABP治疗。比较两组的临床疗效、心肾功能指标、心肌酶谱指标、利钠肽指标、肾功能指标、临床指标及死亡率。结果:观察组临床治疗总有效率为83.33%,明显高于对照组的56.67%,差异有统计学意义(P<0.05)。观察组的左心室射血分数(LVEF)、收缩压、舒张压指标均高于对照组,左室舒张末期内径(LVEDD)、心率均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组超敏肌钙蛋白(hs-cTn)、肌酸激酶同工酶(CK-MB)、肌红蛋白(Mb)指标均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组B型利钠肽(BNP)、N末端B型利钠肽原(NT-proBNP)均明显低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组血肌酐、估算的肾小球滤过率(eGFR)均明显低于对照组,而24 h尿量明显高于对照组,差异有统计学意义(P<0.05)。观察组发热、肢端湿冷、乏力、心悸等临床症状消失时间及住院时间明显优于对照组,差异有统计学意义(P<0.05);观察组死亡率为3.33%,明显低于对照组的33.33%,差异有统计学意义(P<0.05)。结论:IABP辅助治疗急性重症心肌炎可有效提升临床效果,对患者的心肾功能有较好的改善作用。Objective:To investigate the efficacy of intra-aortic balloon pump(IABP)on acute severe myocarditis and its value in improving cardiac and renal function.Method:A total of 60 patients with acute severe myocarditis admitted to the First People's Hospital of Zhaoqing City from January 2019 to December 2021 were selected as the research subjects,and they were divided into observation group and control group by random number table method,30 cases in each group.The control group was given routine treatment,and the observation group was treated with IABP on the basis of the control group.The clinical efficacy,cardiac and renal function indexes,myocardial zymogram indexes,natriuretic peptide indexes,renal function indexes,clinical indexes and mortality were compared between the two groups.Result:The total effective rate of clinical treatment in the observation group was 83.33%,significantly higher than 56.67%in the control group,the difference was statistically significant(P<0.05).The indexes of left ventricular ejection fraction(LVEF),systolic blood pressure,and diastolic blood pressure in the observation group were higher than those in the control group,while the left ventricular end diastolic diameter(LVEDD)and heart rate in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the indexes of high-sensitivity cardiac troponin(hs-cTn),creatine kinase isoenzyme(CK-MB),and myoglobin(Mb)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the B-type natriuretic peptide(BNP)and N-terminal B-type natriuretic peptide(NT-proBNP)in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the blood creatinine and estimated glomerular filtration rate(eGFR)in the observation group were significantly lower than those in the control group,while the 24 h urine volume was sign

关 键 词：主动脉内球囊反搏 急性重症心肌炎 心肾功能 改善价值 

分 类 号：R542.21[医药卫生—心血管疾病]