Visible Light-Induced C-5 Selective C-H Radical Borylation of Imidazo[1,2-a]pyridines with NHC-Boranes  

作　　者：Huitao Zheng Hao Lu Chaobo Su Runlong Yang Limin Zhao Xiang Liu Hua Cao 

机构地区：[1]School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering&Technology Research Center,Guangdong Pharmaceutical University,Zhongshan,Guangdong 528458,China

出　　处：《Chinese Journal of Chemistry》2023年第2期193-198,共6页中国化学（英文版）

基　　金：This work was supported by the Innovation and Strong School Project of Guangdong Pharmaceutical University(2021ZDzX2028);the Scientific and Technological Innovation Leading Talent Project of Zhongshan City(LJ2021009);a Start-up Grant from Guangdong Pharmaceutical University(Grant Nos.51361303,51361304).

摘　　要：A visible-light-induced C-5 selective C-H borylation of imidazo[1,2-a]pyridines with NHC-BH3 via Minisci-type radical borylation re-action has been developed for the first time.The present sustainable protocol provides a new family of regioselectively C5-borylated imidazopyridines that would otherwise be difficult to prepare.It is a supplement to site-selective borylation of azines(nitrogen-con-taining aromatic heterocycles)and the assembly of sp2 carbon-boron bond.

关 键 词：PHOTOCHEMISTRY Boron C-H activation Imidazo[12-a]pyridines RADICALS Synthetic methods 

分 类 号：O62[理学—有机化学]