2012-2021年常州市发热伴血小板减少综合征流行特征及聚集性疫情分析  

ANALYSIS OF EPIDEMIOLOGICAL CHARACTERISTICS AND THE FIRST CLUSTER INFECTIONS OF SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME IN CHANGZHOU CITY FROM 2012 TO 2021

作　　者：王晗 赵立凡 孙刚[3] 曹淦 胡飞飞[5] 褚宏亮[6] 田诚[4] 蒋霞 杨晓[4] WANG Han;ZHAO Li-fan;SUN Gang;CAO Gan;HU Fei-fei;CHU Hong-liang;TIAN Cheng;JIANG Xia;YANG Xiao(School of Public Health,Nanjing Medical University,Nanjing 211103,Jiangsu,China;Department of Laboratory,Changzhou Xinbei District Center for Disease Control and Prevention,Changzhou 213002,Jiangsu,China;Department of Acute Infectious Disease Prevention and Control,Liyang Center for Disease Control and Prevention,Changzhou 213300,Jiangsu,China;Department of Acute Infectious Disease Prevention and Control,Changzhou Center for Disease Control and Prevention,Changzhou 213022,Jiangsu,China;Department of Health Emergency Response,Changzhou Center for Disease Control and Prevention,Changzhou 213022,Jiangsu,China;Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 211103,Jiangsu,China)

机构地区：[1]南京医科大学公共卫生学院,南京211103 [2]常州市新北区疾病预防控制中心检验科,江苏常州213002 [3]溧阳市疾病预防控制中心急性传染病防制科,江苏常州213300 [4]常州市疾病预防控制中心急性传染病防制科,江苏常州213022 [5]常州市疾病预防控制中心卫生应急科,江苏常州213022 [6]江苏省疾病预防控制中心,南京211103

出　　处：《寄生虫与医学昆虫学报》2023年第1期1-5,共5页Acta Parasitologica et Medica Entomologica Sinica

基　　金：溧阳市社会发展项目(LC2020003);中国疾病预防控制中心公共卫生领域卫生健康标准化前期研究项目(BZ2022-Q046)。

摘　　要：为了解常州市发热伴血小板减少综合征(SFTS)的流行病学特征,并调查2021年首起聚集性疫情,为该病的有效监测和防控提供依据,采用描述性流行病学方法对常州市2012—2021年SFTS病例数据进行回顾性分析,同时采用个案调查收集聚集性疫情所涉及病例相关资料。结果显示,2012—2021年常州市共报告SFTS病例20例,其中男性9例,女性11例,男女性别比为0.821;病例主要集中于50~69岁,职业以农民和家务及待业人员为主;发病高峰出现在6~8月,病例分布在溧阳市、金坛区和武进区;发病至诊断时间天数为0~54 d,中位数为10.50 d,就诊医疗机构均为地市级及以上。本起聚集性疫情2例病例发热伴血小板减少综合征布尼亚病毒(SFTSV)核酸阳性,4份首发病例密切接触者血清标本SFTSV总抗体均为阴性,1份犬血清和2份羊血清SFTSV总抗体阳性,家养犬体表寄生蜱SFTSV核酸阴性。结果表明,常州市SFTS病例散在发生,具有一定的地域性和季节性。高危人群为高龄农民,高发季节应加强个人防护和防病意识,早诊断、早治疗。溧阳、金坛等丘陵地区为防控重点地区,应加强预警预测。To understand the epidemiological characteristics of sever fever with thrombocytopenia syndrome(SFTS)cases involved in an aggregated outbreak in 2021 in Changzhou city,so as to provide a basis for effective monitoring,prevention and control of the disease.A descriptive epidemiological method was used to retrospectively analyze these historic SFTS cases from 2012 to 2021,at the same time,case investigation was performed to collect the relevant data of cases involved in the cluster epidemic for providing a basis for effective surveillance,prevention and control of the disease.As results,during 2012-2021,a total of 20 SFTS cases were reported in Changzhou City,9 males and 11 females,with sex ratio of 0.82∶1.These cases occurred sporadically,mainly concentrated in the age ranged of 50-69 years old,and the occupations mainly covered farmers,house workers and unemployed.The cases′number peaked from June to August annually,and distributed in Liyang City,Jintan District and Wujin District.The days from onset to confirmed diagnosis ranged from 0 to 54 days,with a median of 10.50 days,and all medical services were given at the prefectural level or above.Two cases in this outbreak were demonstrated positive nucleic acid for SFTSV,four close contacts of the index case were negative for total SFTSV antibodies,one pet dog serum and two sheep serum were positive for total SFTSV antibodies,and all parasite ticks on pet dogs were negative nucleic acid for SFTSV.The high-risk individuals clustered in senior farmers,whose awareness of disease prevention and personal protection should be strengthened,and accurate diagnosis and proper administration as soon as possible would be paramount important to prevent and control SFTS in the endemic area.Residents in Liyang,Jintan and other hilly area are in high exposure risk and should be trained to avoid infection.

关 键 词：发热伴血小板减少综合征 流行特征 聚集性 常州市 

分 类 号：R181.3[医药卫生—流行病学] R512.8[医药卫生—公共卫生与预防医学]