瑶药小马胎药材质量标准初探  

Preliminary Study of the Quality Standard of Yao Medicine Ardisiae Fordii Herba

作　　者：龚小妹[1] 吴佩莹 欧春丽 韦桂丽 莫单丹[1] 赵以民[1] 周小雷[1] 王硕[1] 候小利 GONG Xiaomei;WU Peiying;OU Chunli;WEI Guili;MO Dandan;ZHAO Yimin;ZHOU Xiaolei;WANG Shuo;HOU Xiaoli(Institute of Guangxi Medicinal Plant,Nanning,Guangxi,China 530023;Guangxi Medical University,Nanning,Guangxi,China 530021)

机构地区：[1]广西壮族自治区药用植物园,广西南宁530023 [2]广西医科大学,广西南宁530021

出　　处：《中国药业》2023年第9期57-61,共5页China Pharmaceuticals

基　　金：广西壮族自治区食品药品监督管理局《广西壮药质量标准》质量评价与标准研究项目[MZY2015004,MZY2017003]。

摘　　要：目的建立瑶药小马胎的质量标准。方法采用显微观察、薄层色谱法对产自广西不同地区的瑶药小马胎进行性状鉴别,按2020年版《中国药典(四部)》通则测定瑶药小马胎浸出物、总灰分、酸不溶性灰分和水分。结果与对照药材比较,瑶药小马胎的形态特征,根茎、茎横切面及粉末显微特征无显著差异,甲醇提取物薄层色谱主要特征斑点无显著差异。瑶药小马胎的总灰分为5.16%~13.19%,酸不溶性灰分为0.83%~5.73%,70%乙醇浸出物为11.74%~19.18%,水分为7.91%~13.32%。结论所建立的瑶药小马胎质量标准可行,拟订其总灰分不得过14.0%,酸不溶性灰分不得过6.0%,70%乙醇浸出物不得少于11.0%,水分不得过14.0%。Objective To establish the quality standard of Yao medicine Ardisiae Fordii Herba.Methods The characteristics of Yao medicine Ardisiae Fordii Herba produced in different areas of Guangxi Zhuang Autonomous Region were identified by the microscopic observation and thin-layer chromatography(TLC)method,and the contents of extract,total ash,acid-insoluble ash and water of Yao medicine Ardisiae Fordii Herba were determined according to the general rules of the Chinese Pharmacopoeia(2020 Edition,VolumeⅣ).Results Compared with those of the reference medicinal material,there was no significant difference in the morphological characteristics,microscopic characteristics of transverse sections of rhizomeand stem and powder of Yao medicine Ardisiae Fordii Herba,as well as the main characteristic spots in the TLC chromatogram of Yao medicine Ardisiae Fordii Herba extract by methanol.The total ash content of Yao medicine Ardisiae Fordii Herba was in the range of 5.16%-13.19%,the acid-insoluble ash content was in the range of 0.83%-5.73%,the content of extract by 70%ethanol was in the range of 11.74%-19.18%,and the water content was in the range of 7.91%-13.32%.Conclusion The established quality standard of Yao medicine Ardisiae Fordii Herba is feasible,and the proposed quality standard are as follows:the total ash content of Yao medicine Ardisiae Fordii Herba should not be more than 14.0%,the acid-insoluble ash content should not be more than 6.0%,the extract by 70%ethanol should not be less than 11.0%,and the moisture content should not be more than 14.0%.

关 键 词：瑶药小马胎 性状鉴别 质量标准 

分 类 号：R932[医药卫生—生药学] R284.1[医药卫生—药学] R286.0