综合疗法在勃起功能障碍合并2型糖尿病吸烟患者中的疗效及影响因素分析  

Analysis of the curative effect and influencing factors of comprehensive therapy in erectile dysfunctional patients with smoking and type 2 diabetes mellitus

作　　者：常翔 张媛君 权金星[1] 刘静[1] 刘菊香[1] Chang Xiang;Zhang Yuanjun;Quan Jinxing;Liu Jing;Liu Juxiang(Department of Endocrinology,Gansu Provincial Hospital,Lanzhou 730000,China;Department of Endocrinology,Wuwei People's Hospital,Wuwei 733000,Gansu,China)

机构地区：[1]甘肃省人民医院内分泌科,甘肃兰州730000 [2]甘肃省武威市人民医院内分泌科,甘肃武威733000

出　　处：《兰州大学学报（医学版）》2023年第3期57-62,共6页Journal of Lanzhou University（Medical Sciences）

基　　金：甘肃省自然科学基金资助项目(20JR5RA155)。

摘　　要：目的 探讨综合疗法在勃起功能障碍(ED)合并2型糖尿病(T2DM)吸烟患者中的疗效及影响因素。方法 选取2018年2月-2021年3月甘肃省武威市人民医院内分泌科收治的30~56岁ED合并T2DM吸烟的已婚患者198例,随机分为对照组、治疗组,其中对照组97例,治疗组101例,记录患者一般资料、问询生活习惯后进行国际勃起功能指数(IIEF-5)问卷评分,给予综合治疗2周后再次进行IIEF-5问卷评分,对比分析综合疗法在ED合并T2DM吸烟患者中的疗效及影响因素。结果 治疗组给予综合治疗后IIEF-5总评分和各问题的评分均显著高于对照组,差异有统计学意义(P<0.05),影响其治疗有效性的常见因素为T2DM病程、年龄及体重指数,是否饮酒、糖化血红蛋白、空腹血糖、24 h尿蛋白、治疗后空腹血糖等因素对ED疗效的改善差异无统计学意义(P> 0.05)。结论 在吸烟的T2DM患者中ED是常见的合并症。T2DM病程、年龄和体重指数是影响吸烟的T2DM合并ED患者治疗有效性的危险因素。Objective To explore the curative effect and influencing factors of comprehensive therapy in erectile dysfunction(ED)patients with smoking and type 2 diabetes mellitus(T2DM).Methods From February 2018 to March 2021,198 married male ED patients with smoking and T2DM were randomly assigned to the Department of Endocrinology,Wuwei People's Hospital in Wuwei,Gansu,with 97 in the control group and 101 in the treatment group.An international index of erectile function-5(IIEF-5)questionnaire was scored after observing the general information of the patients and inquiring about their living habits,and an IIEF-5 questionnaire was scored again after 2 weeks of comprehensive treatment,in order to analyze the curative effect and influencing factors of comprehensive therapy in ED patients with smoking and T2DM.Results The treatment group's total IIEF-5 score and scores for each question were significantly higher than those in the control group,the difference being statistically significant(P<0.05).The common factors affecting the effectiveness of treatment were the course of T2DM,age and body mass index(P<0.05).Whether they drank alcohol or not,their glycated hemoglobin,fasting blood glucose,24-h urinary albumin,fasting blood glucose after treatment had no statistically significant improvement in the efficacy of ED with smoking and T2DM patients(P>0.05).Conclusion In T2DM smokers, ED wasw a common complication. The course of T2DM, age, and body massindex were the risk factors affecting the effectiveness of T2DM smoking combined with ED treatment.

关 键 词：勃起功能障碍 2型糖尿病 吸烟 疗效 影响因素 

分 类 号：R446.1[医药卫生—诊断学]