化妆品过敏相关不良反应的诊断新进展与挑战  

New progress and challenges in the diagnosis and treatment of cosmetic allergy-related adverse reactions

作　　者：张冲 仲少敏[1] 吴艳[1] 赵嘉惠[1] 赵作涛[1] 田燕 李航[1] Zhang Chong;Zhong Shaomin;Wu Yan;Zhao Jiahui;Zhao Zuotao;Tian Yan;Li Hang(Department of Dermatology,Peking University First Hospital,National Clinical Research Center for Skin and Immune Diseases,Beijing Key Laboratory of Molecular Diagnosis on Dermatoses,National Medical Products Administration(NMPA)Key Laboratory for Quality Control and Evaluation of Cosmetics,Beijing 100034,China;Department of Dermatology and Venereal Diseases,Air Force Medical Center of PLA,Beijing 100142,China)

机构地区：[1]北京大学第一医院皮肤科,国家皮肤与免疫疾病临床医学研究中心,皮肤病分子诊断北京市重点实验室,国家药品监督管理局化妆品质量控制与评价重点实验室,北京100034 [2]中国人民解放军空军特色医学中心皮肤病与性病科,北京100142

出　　处：《中华预防医学杂志》2023年第4期591-596,460,共7页Chinese Journal of Preventive Medicine

摘　　要：我国现行的化妆品不良反应相关皮肤疾病诊治标准(GB/T 17149.1-1997)由原卫生部与国家技术监督局于1997年联合发布,其中把变应性接触性皮炎及光变应性皮炎等列为化妆品过敏相关不良反应。近20年来化妆品行业快速发展,化妆品使用量的增加和化妆品成分、配方的不断变化都导致化妆品过敏性不良反应发生率显著升高,临床表现也更加多样化。近年有很多对化妆品过敏特殊表现以及化妆品过敏原检测结果的报道,为后续完善化妆品过敏相关不良反应的诊断与预防提供了借鉴。In China,the current standard for cosmetic adverse reactions related skin disease(GB/T 17149.1-1997)was jointly issued by the Ministry of Health and the State Bureau of Technical Supervision in 1997,cosmetic-allergic adverse reactions include allergic contact dermatitis and photo-allergic contact dermatitis according to this standard.The increasing use and changes in cosmetic ingredients or formula lead to a significant increase for the incidence of adverse reactions as the cosmetics industry is developing rapidly in the last 20 years.In the meantime,the clinical manifestations have become more diverse.In recent years,there have been many reports on the special manifestations for cosmetic allergy and allergen test,which provide a reference for the subsequent improvement of the diagnosis and prevention.

关 键 词：化妆品 过敏 斑贴试验 监管科学 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]