重复经颅磁刺激疗法联合康复训练对外伤性脊髓损伤患者疼痛程度及生活质量的影响  

Effects of repetitive transcranial magnetic stimulation therapy combined with rehabilitation training on pain degree and quality of life in patients with traumatic spinal cord injury

作　　者：高志云 钟小溪 王娟 GAO Zhiyun;ZHONG Xiaoxi;WANG Juan(Yulin No.2 Hospital,Yulin 719000,China)

机构地区：[1]榆林市第二医院,陕西榆林719000

出　　处：《临床医学研究与实践》2023年第14期13-16,共4页Clinical Research and Practice

摘　　要：目的探讨重复经颅磁刺激(rTMS)疗法联合康复训练在外伤性脊髓损伤(SCI)患者中的应用效果。方法选取2020年1月至2021年1月收治的90例外伤性SCI患者作为研究对象,按照随机数字表法将其分为对照组和观察组,每组45例。对照组接受常规康复训练,观察组在常规康复训练的基础上接受rTMS疗法。比较两组的疼痛程度、睡眠质量、血清指标、生活质量、运动功能和日常生活活动能力。结果治疗后,两组的简化Mcgill疼痛问卷(SF-MPQ)各部分评分和匹兹堡睡眠质量指数(PSQI)评分均低于治疗前,且观察组低于对照组(P<0.05)。治疗后,两组的胎肝激酶-1(FLK-1)、神经生长因子(NGF)水平均高于治疗前,S-100β水平低于治疗前,且观察组显著优于对照组(P<0.05)。治疗后,两组的生活质量综合评定问卷(GQOLI-74)各维度评分均高于治疗前,且观察组高于对照组(P<0.05)。治疗后,两组的功能独立性量表(FIM)、改良Barthel指数(MBI)评分与10 m步行测试(10MWT)速度均高于治疗前,且观察组高于对照组(P<0.05)。结论rTMS疗法联合康复训练能够缓解外伤性SCI患者的疼痛程度,改善睡眠质量,一定程度促进患者下肢功能的恢复,提高生活质量。Objective To explore the application effect of repetitive transcranial magnetic stimulation(rTMS)therapy combined with rehabilitation training in patients with traumatic spinal cord injury(SCI).Methods A total of 90 patients with traumatic SCI admitted from January 2020 to January 2021 were selected as the research objects and divided into control group and observation group according to the random number table method,with 45 cases in each group.The control group received routine rehabilitation training,and the observation group received rTMS therapy on the basis of routine rehabilitation training.The pain degree,sleep quality,serum indexes,quality of life,motor function and ability of activites of daily living of the two groups were compared.Results After treatment,the each part score of Short-Form of Mcgill Pain Questionnaire(SF-MPQ)and score of Pittsburgh Sleep Quality Index(PSQI)in the two groups were lower than those before treatment,and those in the observation group were lower than the control group(P<0.05).After treatment,the levels of fetal liver kinase-1(FLK-1)and never growth factor(NGF)in the two groups were higher than those before treatment,the level of S-100βwas lower than that before treatment,and those of the observation group were significantly better than the control group(P<0.05).After treatment,the scores of each dimension of Generic Quality of Life Inventory-74(GQOLI-74)in the two groups were higher than those before treatment,and those in the observation group were higher than the control group(P<0.05).After treatment,the scores of Functional Independence Measure(FIM),modified Barthel Index(MBI)and 10 m walking test(10MWT)speed in the two groups were higher than those before treatment,and those in the observation group were higher than the control group(P<0.05).Conclusion The rTMS therapy combined with rehabilitation training can relieve the pain degree of patients with traumatic SCI,improve sleep quality,promote the recovery of lower limb function to a certain extent,and enhance the quali

关 键 词：外伤性脊髓损伤 康复训练 重复经颅磁刺激 疼痛程度 生活质量 

分 类 号：R493[医药卫生—康复医学]