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作 者:陈瑞鑫 詹琥珀 康点点 蒋桂华[1,2,3] 蒋运斌 CHEN Ruixin;ZHAN Hupo;KANG Diandian;JIANG Guihua;JIANG Yunbin(Chengdu University of Traditional Chinese Medicine,School of Pharmacy,Chengdu 611137,China;Chengdu University of Traditional Chinese Medicine,State Key Laboratory of Southwestern Chinese Medicine Resources,Chengdu 611137,China;Chengdu University of Traditional Chinese Medicine,School of Ethnic Medicine,Chengdu 611137,China;College of Pharmaceutical Sciences and Chinese Medicine,Southwest University,Chongqing 400715,China)
机构地区:[1]成都中医药大学药学院,成都611137 [2]成都中医药大学西南特色中药资源国家重点实验室,成都611137 [3]成都中医药大学民族医药学院,成都611137 [4]西南大学药学院·中医药学院,重庆400715
出 处:《中国现代应用药学》2023年第6期856-864,共9页Chinese Journal of Modern Applied Pharmacy
基 金:国家自然科学基金项目(82104528);重庆市自然科学基金面上项目(cstc2020jcyj-msxmX0146)。
摘 要:独一味为青藏高原珍贵药用植物,是中国藏、蒙、纳西等民族民间常用草药之一,中国药典2020年版载其具有活血止血、祛风止痛的功效。类风湿关节炎是风湿免疫科的常见疾病,全球发病率已达1%,且目前在国内外均缺乏特效治疗方法。研究表明,中医药和藏药在延缓类风湿关节炎骨破坏等方面具有疗效好、不良反应少、长期适用等优点,中藏药独一味作为祛风止痛的药物具有良好的防治类风湿关节炎的潜力和发展前景。因此,本研究对独一味防治类风湿关节炎的相关本草记载和研究现状进行总结,旨在为临床使用独一味治疗类风湿关节炎提供一定的理论依据。Lamiophlomis rotata(Benth.)Kudo(LR)is a precious medicinal plant on the Qinghai-Tibet Plateau.It is one of the commonly used herbal medicines in Tibetan,Mongolian,Naxi and other ethnic groups in China.Chinese Pharmacopoeia 2020 Edition states that it has the effects of promoting blood circulation and stopping bleeding,dispelling wind and relieving pain.Rheumatoid arthritis is a common disease in the Department of Rheumatology and Immunology,with a global incidence of 1%,there is no effective treatment method at home and abroad.Studies have shown that traditional Chinese medicine and Tibetan medicine have the advantages of good curative effect,few adverse reactions,and long-term application in delaying bone destruction in rheumatoid arthritis.LR is a drug for expelling wind and relieving pain,which have good potential and development prospects for the prevention and treatment of rheumatoid arthritis.Therefore,this study intends to summarize the related herbal records and research status of the LR for the prevention and treatment of rheumatoid arthritis,in order to provide a certain theoretical basis for the clinical use of the unique medicine for the treatment of rheumatoid arthritis.
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