从“变蒸学说”探析低出生体重儿追赶生长与胰岛素抵抗  

Analysis of Catch-Up Growth and IR of Low Birth Weight Infants from‘Bianzheng Theory’

作　　者：牛苗苗 张效科[1] 段玉红 张艺馨 屠晓晓 NIU Miaomiao;ZHANG Xiaoke;DUAN Yuhong;ZHANG Yixin;TU Xiaoxiao(Shaanxi University of Chinese Medicine,Xianyang 712046,China;Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)

机构地区：[1]陕西中医药大学,陕西咸阳712046 [2]陕西中医药大学附属医院,陕西咸阳712000

出　　处：《中医药学报》2023年第5期6-10,共5页Acta Chinese Medicine and Pharmacology

基　　金：国家自然科学基金项目(81774304);陕西省教育厅重点项目(19JZ027)。

摘　　要：低出生体重儿(LBWI)自出生起即面临身心及各器官发育不成熟等问题,追赶生长是其达到正常生长发育及代谢的重要方式,但同时亦会引起胰岛素抵抗(IR)及其远期代谢性疾病(如2型糖尿病、肥胖、代谢综合征等)的发生。“变蒸学说”作为追赶生长的中医理论基础,从“变蒸学说”探讨追赶生长发生的生理及病理意义,对于中医药防治小儿早期发生IR及降低其远期代谢性疾病发生的风险人群具有重要意义。Low birth weight infants(LBWI)are faced with immaturity of body,mind and organs from birth.Catch-up growth is an important way to achieve normal growth and development,but at the same time it will also cause insulin resistance(IR)and the occurrence of long-term metabolic diseases(type 2 diabetes,obesity,metabolic syndrome).‘Bianzheng theory’is the theoretical basis of catch-up growth in TCM.From then on,it is of great significance to discuss the physiological and pathological significance of catch-up growth,and is of great significance for Chinese medicine to prevent and treat early IR in children and reduce the risk of long-term metabolic diseases.

关 键 词：低出生体重儿 变蒸学说 追赶生长 胰岛素抵抗 

分 类 号：R272.1[医药卫生—中医儿科学]