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作 者:李姗珊 史宝林[2] 刘晓艳 白骏北[3] 董成 韩聚强 LI Shan-shan;SHI Bao-lin;LIU Xiao-yan;BAI Jun-bei;DONG Cheng;HAN Ju-qiang(The Seventh Medical Centre,Chinese PLA General Hospital,Beijing 100700,China;Laboratory Medicine College,Hebei North University,Zhangjiakou,Hebei 075132,China;Beijing Research Institute of Sports Science,Beijing 100075,China)
机构地区:[1]解放军总医院第七医学中心,北京100700 [2]河北北方学院医学检验学院,河北张家口075132 [3]北京市体育科学研究所,北京100075
出 处:《军事医学》2023年第3期223-227,共5页Military Medical Sciences
基 金:军委科技委重大专项(19-163-12-ZD-037-002-01)。
摘 要:目的探讨高原驻训对官兵血红蛋白(Hb)含量的影响规律及特点分析。方法选取两个独立研究队列,分别抽取外周静脉血,检测血常规、肝功能、肾功能及电解质等基础生化指标,并进行统计学分析。结果高原驻训对官兵机体影响最敏感的指标是Hb含量,进驻高原2周Hb含量升至较高水平(173.43±20.73)g/L;随着从高原返回平原地区,Hb含量2周内恢复正常水平(148.97±13.12)g/L;高原驻训时间在1年内官兵Hb含量与驻训时间存在显著时效关系,而高原驻训时间大于1年的官兵Hb含量将维持在较高异常水平;Hb含量的变化与机体肝、肾功能等基础生化指标无关。结论Hb含量是影响高原驻训官兵机体生理功能最敏感指标之一,这为今后精准高原卫勤保障提供了重要依据。Objective To investigate the way in which hemoglobin(Hb)contents change in soldiers under training on the plateau.Methods Two independent cohorts were selected in this study.Peripheral vein blood was aseptically taken to test the blood routine,liver function,renal function,main electrolytes and other basic biochemical indexes.Results Hb content was one of the most sensitive markers in soldiers trained on the plateau.Hb contents quickly increased significantly(173.43±20.73)g/L in those soldiers within 2 weeks of training on the plateau.After those soldiers returned to the plains,Hb contents returned to normal(148.97±13.12)g/L within 2 weeks.Furthermore,a significant time-effect correlation was found between Hb contents and duration of training time on the plateau within one year.However,after over one year of training on the plateau,this time-effect correlation disappeared and Hb contents of the soldiers remained at an abnormally high level.Additionally,Hb contents changed independently of the basic biochemical indexes.Conclusions A Hb content is one of the most sensitive indicators to affect the physiological function of soldiers during training on the plateau,which can contribute to precise medical support at a high altitude.
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