Saccades of video head impulse test in Meniere's disease and Vestibular Migraine: What can we learn from?  

作　　者：Yi Du Xingjian Liu Lili Ren Yu Wang Fei Ji Weiwei Guo Ziming Wu 

机构地区：[1]College of Otolaryngology Head and Neck Surgery,Chinese PLA General Hospital,Chinese PLA Medical School,28 Fuxing Road,Beijing,China [2]National Clinical Research Center for Otolaryngologic Diseases,Beijing,China [3]State Key Lab of Hearing Science,Ministry of Education,Beijing,China [4]Beijing Key Lab of Hearing Impairment Prevention and Treatment,Beijing,China

出　　处：《Journal of Otology》2023年第2期79-84,共6页中华耳科学杂志（英文版）

基　　金：supported by grants from National Key Research and Development Program of China-part3(2020YFC2005203);Capital's Funds for Health Improvement and Research(No.2022-1-2023).

摘　　要：Background:Saccades are often observed on video head impulse tests(vHIT)in patients with Meniere's Disease(MD)and Vestibular Migraine(VM).However,their saccadic features are not fully described.Objective:This study aims to identify the saccades characteristics of MD and VM.Methods:75 VM patients and 103 definite unilateral MD patients were enrolled in this study.First raw saccades were exported and analyzed.The VM patients were divided into left and right based on their ears,while the MD patients were separated into affected and unaffected subgroups based on their audiograms and symptoms.Results:The MD patients have more saccades on the affected side(85%vs.69%),and saccade velocity is more consistent than the contralateral side(shown by the coefficient of variation).The saccades occurrence rates on both sides are similar in VM(77%vs.76%),as are other saccadic parameters.The MD patients have more significant inter-aural differences than the VM patients,manifested in higher velocity(p-value 0.000),earlier arriving(p-value 0.010),and more time-domain gathered(p-value 0.003)on the affected side.Conclusions:Bilateral saccades are commonly observed in MD and VM.In contrast to MD,saccades on VM are subtle,scattered,and late-arrived.Furthermore,the MD patients showed inconsistent saccadic distribution with more velocity-uniform saccades on the affected side.

关 键 词：Meniere's disease Vestibular migraine SACCADES Video head impulse test Differential diagnosis 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]