Ultrasoft,sensitive fiber-like sensor by assembly of bacterial cellulose(BC)nanofibrils and BC molecules for biocompatible strain sensing  

作　　者：Si Meng Yuyan Zhang Nihuan Wu Cheng Peng ZhiYao Huang Zhengjie Lin Cheng Qi Zhou Liu Tiantian Kong 

机构地区：[1]College of Chemistry and Environmental Engineering,Shenzhen University,Shenzhen 518000,China [2]Department of Biomedical Engineering,School of Medicine,Shenzhen University,Shenzhen 518000,China [3]D Printing Clinical Translational and Regenerative Medicine Center,Shenzhen Qianhai Shekou Free Trade Zone Hospital,Shenzhen 518067,China [4]College of Mechatronics and Control Engineering,Shenzhen University,Shenzhen 518000,China [5]Department of Urology,Inst Translat Med,The First Affiliated Hospital of Shenzhen University,Shenzhen Second People’s Hospital,Shenzhen 518000,China

出　　处：《Nano Research》2023年第3期4067-4076,共10页纳米研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.52172283 and 22078197);Guangdong Basic and Applied Basic Research Foundation(Nos.2021A1515012506,2020A1515110480,2022A1515011815,and 2019A1515111156).

摘　　要：The development of implantable bioelectronics is driven by emerging applications including continuous health monitoring and human-machine interfacing.The mechanical mismatch between implanted bioelectronics and tissues not only compromises device accuracy,but also causes interference with tissues undesirably.To address this issue,it is necessary to develop ultrasoft and biocompatible fiber strain sensor with proper stretchability and sensitivity.Here,we fabricate a bacterial cellulose-based sensing fiber which possesses the stretchability and elastic modulus(~102 kPa)close to those of soft tissues.In addition,such fiber has high sensitivity to tiny tensile force/strain(8.8×10^(−3)N/2.5%)and low cell cytotoxicity.These excellent properties make the bacterial cellulose(BC)-based sensing fiber an excellent candidate of implantable bioelectric devices for monitoring subtle motions of organs.We demonstrate this by applying it for continuous monitoring of human pulse and bullfrog heartbeats.The(BC/oxBC)@PANI(ox=oxidized and PANI=polyaniline)fibers can further be woven into an array sensor and serve more complex sensing functions,such as multipoint force perception and shape recognition as demonstrated.

关 键 词：BIOELECTRONICS fiber bacteria cellulose SPINNING SENSOR 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]