Metal-organic frameworks based surface-enhanced Raman spectroscopy technique for ultra-sensitive biomedical trace detection  

作　　者：Yuna Zhang Cuili Xue Yuli Xu Shengsheng Cui Alexander A.Ganeev Kistenev Yury V Anna Gubal Victoria Chuchina Han Jin Daxiang Cui 

机构地区：[1]Department of Instrument Science and Engineering,School of Electronic Information and Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China [2]St Petersburg University,7/9 Universitetskaya Emb.,St Petersburg 199034,Russia [3]Tomsk State University,Lenina Av.36,Tomsk,Tomsk 634050,Russia [4]National Engineering Research Center for Nanotechnology,Shanghai 200241,China

出　　处：《Nano Research》2023年第2期2968-2979,共12页纳米研究（英文版）

基　　金：supported by the National Basic Research Program of China(No.2017YFA0205304);the National Natural Science Foundation of China(Nos.82020108017 and 81921002);the Shanghai Sailing Program(No.22YF1431100);the Medical Engineering Cross Project of Shanghai Jiao Tong University(Nos.YG2016ZD10,ZH2018QNA51,and ZH2018QNA28);supported by the“Belt and Road”Young Scientist Exchange Program of the Science and Technology Commission of Shanghai(No.18410741600);the Shanghai Science Foundation(No.20142201300).

摘　　要：Metal-organic frameworks(MOFs)have attracted widespread interest due to their unique and unprecedented advantages in microstructures and properties.Besides,surface-enhanced Raman scattering(SERS)technology has also rapidly developed into a powerful fingerprint spectroscopic technique that can provide rapid,non-invasive,non-destructive,and ultra-sensitive detection,even down to single molecular level.Consequently,a considerable amount of researchers combined MOFs with the SERS technique to further improve the sensing performance and broaden the applications of SERS substrates.Herein,representative synthesis strategies of MOFs to fabricate SERS-active substrates are summarized and their applications in ultra-sensitive biomedical trace detection are also reviewed.Besides,relative barriers,advantages,disadvantages,future trends,and prospects are particularly discussed to give guidance to relevant researchers.

关 键 词：metal-organic framework(MOF) surface-enhanced Raman scattering(SERS) synthesis strategy biomedical trace detection 

分 类 号：O64[理学—物理化学]