Light-responsive organic artificial enzymes:Material designs and bio-applications  

作　　者：Weili Wang Qing Shen Hao Cai Leichen Wang Jinjun Shao Wenjun Wang Xiaochen Dong 

机构地区：[1]Key Laboratory of Flexible Electronics(KLOFE)and Institute of Advanced Materials(IAM),Nanjing Tech University(NanjingTech),Nanjing 211816,China [2]School of Physical Science and Information Technology,Liaocheng University,Liaocheng 252059,China

出　　处：《Nano Research》2023年第1期117-126,共10页纳米研究（英文版）

基　　金：supported by the National Key Research and Development(R&D)Program of China(No.2020YFA0709900);the National Natural Science Foundation of China(Nos.62120106002 and 22175089);the Natural Science Foundation of Jiangsu Province(No.BK20200092);the Natural Science Foundation of Ningbo(No.202003N40448);Research Innovation Plan for Graduate Students in Jiangsu Province(No.SJCX21_0473);“Taishan scholars”construction special fund of Shandong Province.

摘　　要：As significant biocatalysts,natural enzymes have exhibited a vast range of applications in biocatalytic reactions.However,the“always-on”natural enzyme activity is not beneficial for the regulation of catalytic processes,which limits their bio-applications.Recently,it has been extensively reported that various organic artificial enzymes exhibit prominent absorption and controlled activity under illumination,which not only creates a series of light-responsive catalytic platforms but also plays a key role in biosensing and biomedical research.To provide novel ideas for the design of artificial enzymes,we conduct this review to highlight the recent progress of light-responsive organic artificial enzymes(LOA-Enz).The specific photoresponse mechanism and various bio-applications of LOA-Enz are also presented in detail.Furthermore,the remaining challenges and future perspectives in this field are discussed.

关 键 词：light-response organic artificial enzymes catalytic activity bio-applications 

分 类 号：O64[理学—物理化学]