Surface modification of MoS_(2) nanosheets by single Ni atom for ultrasensitive dopamine detection  

作　　者：Xuejiao Sun Cai Chen Can Xiong Congmin Zhang Xusheng Zheng Jin Wang Xiaoping Gao Zhen-Qiang Yu Yuen Wu 

机构地区：[1]College of Chemistry and Environmental Engineering,Institute of Low-dimensional Materials Genome Initiative,Shenzhen University,Shenzhen 518071,China [2]School of Chemistry and Materials Science,University of Science and Technology of China,Hefei 230026,China [3]College of Materials Science and Engineering,Shenzhen University,Shenzhen 518071,China [4]Dalian National Laboratory for Clean Energy,Dalian 116023,China [5]National Synchrotron Radiation Laboratory,University of Science and Technology of China,Hefei 230029,China

出　　处：《Nano Research》2023年第1期917-924,共8页纳米研究（英文版）

基　　金：This work was supported by China Ministry of Science and Technology(No.2021YFA1500404);the Anhui Provincial Natural Science Foundation(Nos.2108085QB70 and 2108085UD06);the DNL Cooperation Fund,CAS(No.DNL201918);the Collaborative Innovation Program of Hefei Science Center,CAS(No.2021HSC-CIP002);the Natural Science Foundation of Hefei,China(No.2021044);the Fundamental Research Funds for the Central Universities(Nos.WK2060000004,WK2060000021,WK2060000025,KY2060000180,and KY2060000195);the Fundamental Research Funds for the Central Universities(No.WK5290000003)。

摘　　要：Single atom catalysts have been recognized as potential catalysts to fabricate electrochemical biosensors,due to their unexpected catalytic selectivity and activity.Here,we designed and fabricated an ultrasensitive dopamine(DA)sensor based on the flower-like MoS_(2) embellished with single Ni site catalyst(Ni-MoS_(2)).The limit of detection could achieve 1 pM in phosphate buffer solution(PBS,pH=7.4),1 pM in bovine serum(pH=7.4),and 100 pM in artificial urine(pH=6.8).The excellent sensing performance was attributed to the Ni single atom axial anchoring on the Mo atom in the MoS_(2) basal plane with the Ni-S_(3) structure.Both the experiment and density functional theory(DFT)results certify that this structural feature is more favorable for the adsorption and electron transfer of DA on Ni atoms.The high proportion of Ni active sites on MoS_(2) basal plane effectively enhanced the intrinsic electronic conductivity and electrochemical activity toward DA.The successful establishment of this sensor gives a new guide to expand the field of single atom catalyst in the application of biosensors.

关 键 词：single atom catalysts MoS_(2) dopamine(DA)sensor serum URINE 

分 类 号：O64[理学—物理化学]