尿干化学亚硝酸盐联合白细胞检测在尿路细菌感染诊断中的效能  

Efficacy of urine dry chemical nitrite combined with white blood cell detection in diagnosis of urinary tract bacterial infection

作　　者：吴冰 WU Bing(Department of Clinical Laboratory of Jinqiu Hospital,Shenyang 110016 Liaoning,China)

机构地区：[1]辽宁省金秋医院检验科,辽宁沈阳110016

出　　处：《中国民康医学》2023年第7期120-122,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨尿干化学亚硝酸盐联合白细胞检测在尿路细菌感染诊断中的效能。方法:选取2019年6月至2021年6月该院收治的200例疑似尿路感染患者进行前瞻性研究,以尿培养结果为金标准,统计尿干化学亚硝酸盐、白细胞单项及联合检测结果,并比较尿干化学亚硝酸盐、白细胞单项及联合检测在尿路感染诊断中的效能。结果:200份尿培养共78份阳性,阳性率为39.00%;其中大肠埃希菌占比最高为38.46%,其次是铜绿假单胞菌为12.82%,粪肠球菌为11.54%,其余细菌均在10%以下;200份尿液标本中31份亚硝酸盐阳性,35份白细胞阳性,106份亚硝酸盐联合白细胞阳性;亚硝酸盐联合白细胞检测诊断尿路感染的灵敏度、特异度、阳性预测值均高于单项检测,差异有统计学意义(P<0.05);亚硝酸盐联合白细胞检测诊断尿路感染的阴性预测值高于白细胞单项检测,差异有统计学意义(P<0.05);亚硝酸盐检测诊断尿路感染的特异度和阳性预测值均高于白细胞检测,差异有统计学意义(P<0.05);亚硝酸盐与白细胞单项检测诊断尿路感染的灵敏度和阴性预测值比较,差异均无统计学意义(P>0.05)。结论:尿干化学亚硝酸盐联合白细胞检测在尿路感染诊断中的效能高于两者单项检测。Objective:To investigate efficacy of urine dry chemical nitrite combined with white blood cell detection in diagnosis of urinary tract bacterial infection.Methods:A prospective study was conducted on 200 patients with suspected urinary tract infection in the hospital from June 2019 to June 2021.Using the results of urine culture as the gold standard,the results of single and combined detection of urine dry chemistry nitrite and white blood cells were statistically analyzed.The efficacies of single and combined detection of urine dry chemistry nitrite and white blood cells in the diagnosis of urinary tract infection were compared.Results:A total of 78 of 200 urine cultures were positive with a positive rate of 39.00%.Among them,Escherichia coli accounted for 38.46%,followed by Pseudomonas aeruginosa of 12.82%,Enterococcus faecalis of 11.54%,and the rest of the bacteria were below 10%.Among the 200 urine samples,31 were positive for nitrite,35 were positive for white blood cells,and 106 were positive for nitrite combined with white blood cells.The sensitivity,the specificity and positive predictive value of nitrite combined with white blood cell detection in the diagnosis of the urinary tract infection were higher than those of single detection,and the differences were statistically significant(P<0.05).The negative predictive value of nitrite combined with white blood cell detection in the diagnosis of urinary tract infection was higher than that of single white blood cell detection,and the difference was statistically significant(P<0.05).The specificity and the positive predictive value of nitrite detection in the diagnosis of urinary tract infection were higher than those of white blood cell detection,and the differences were statistically significant(P<0.05).However,there were no significant differences in the sensitivity and the negative predictive value between single nitrite detection and single white blood cell detection in the diagnosis of urinary tract infection(P>0.05).Conclusions:The efficacy of urine dr

关 键 词：尿干化学 亚硝酸盐 白细胞 检测 诊断 尿路感染 效能 

分 类 号：R695[医药卫生—泌尿科学]