Presentations,treatment and outcomes of unifocal and multifocal osseous appendicular Langerhans cell histiocytosis lesions in a pediatric population  

作　　者：Ekene U Ezeokoli Parker Mitchell Eva Schlehr Neritan Borici Nicole Montgomery 

机构地区：[1]Department of Orthopedic Surgery,Texas Children's Hospital,Houston,Texas,USA [2]Oakland University William Beaumont School of Medicine,Rochester,Michigan,USA [3]Department of Orthopedic Surgery,Baylor College of Medicine,Houston,Texas,USA [4]Baylor College of Medicine,Houston,Texas,USA [5]University at Buffalo Jacobs School of Medicine and Biomedical Sciences,Buffalo,New York,USA

出　　处：《World Journal of Pediatric Surgery》2023年第1期55-57,共3页世界小儿外科杂志（英文）

摘　　要：Langerhans cell histiocytosis(LCH)is a rare disease most commonly presenting in the pediatric population and characterized by neoplastic clonal proliferation of Langerhans dendritic cells with accumulation in various sites,including skeletal and visceral lesions.1 There are three levels of classification per the Histiocyte Society:single-system single-site(SS-s),single-system multiple-site(SS-m),and multisystem(MS).2 SS-s predominantly carries a better prognosis with more conservative treatment while MS requires a more aggressive treatment that is more likely to have an inferior outcome.

关 键 词：LANGERHANS LESIONS TREATMENT 

分 类 号：R726[医药卫生—儿科]