Solitary acral persistent papular mucinosis nodule:A case report and summary of eight Korean cases  

作　　者：Yu Jeong Park Hui Young Shin Woo Kyoung Choi Ai-Young Lee Seung Ho Lee Jong Soo Hong 

机构地区：[1]Department of Dermatology,Dongguk University Ilsan Hospital,College of Medicine,Dongguk University,Goyang-si,Gyeonggi-do,Korea 10326,South Korea

出　　处：《World Journal of Clinical Cases》2023年第13期3086-3091,共6页世界临床病例杂志

摘　　要：BACKGROUND Acral persistent papular mucinosis(APPM)is a rare idiopathic subtype of localized lichen myxedematosus.To date,there have been 40 APPM cases reported worldwide;however,only 7 cases have been reported in the Korean literature.CASE SUMMARY A 70-year-old man was referred to our hospital with a solitary pinkish nodule on the dorsum of his right hand.Despite the absence of symptoms,the patient wanted to know the exact diagnosis;thus,a biopsy was performed.Histopathological examination of a biopsy specimen obtained from the nodule on the dorsum of his hand revealed orthokeratotic hyperkeratosis with patchy parakeratosis,prominent hypergranulosis,and diffuse dissecting mucinous deposition between collagen bundles,along with some bland-looking spindle cells throughout the dermis.The nodule was histologically diagnosed as an APPM,and an intralesional triamcinolone injection(2.5 mg/mL)was started every 2 wk.After three sessions of treatment,the patient showed marked improvements.CONCLUSION To the best of our knowledge,this is the first case of a Korean APPM presenting as a solitary nodule that showed a marked response to triamcinolone intralesional injection.Since it is a rare disease,we report this case to contribute to future research on the pathogenesis and treatment of APPM.

关 键 词：Acral persistent papular mucinosis Localized lichen myxedematosus Cutaneous mucinosis Mucin Case report 

分 类 号：R751[医药卫生—皮肤病学与性病学]