不同时间间隔针刺治疗原发性甲状腺功能亢进症的疗效比较  

Comparison of the efficacies of acupuncture at different time intervals for primary hyperthyroidism

作　　者：谭双[1] 符晓敏[1] TAN Shuang;FU Xiaomin(Beijing University of Traditional Chinese Medicine Huguo Temple Hospital of Traditional Chinese Medicine,Beijing 100035,China)

机构地区：[1]北京中医药大学附属护国寺中医医院,北京100035

出　　处：《上海针灸杂志》2023年第5期453-458,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：北京市西城区卫生健康委员会青年科技人才(科技新星)培养项目(xwkx2020-02)。

摘　　要：目的观察并比较不同时间间隔针刺配合药物治疗原发性甲状腺功能亢进症(原发性甲亢)的临床疗效。方法将111例原发性甲亢患者随机分为A组、B组和C组,每组37例。3组均采用针刺配合口服甲硫咪唑片治疗。A组每周针刺治疗1次,B组每周治疗2次,C组每周治疗3次。治疗24周后,观察3组治疗前后各项甲状腺激素[促甲状腺素(thyroid stimulating hormone,TSH)、游离三碘甲状腺原氨酸(free triiodothyronine,FT3)、游离甲状腺素(free thyroxine,FT4)]水平、静息状态下心率及各项中医症状体征评分的变化情况,并比较3组临床疗效。结果3组治疗后各项甲状腺激素水平、静息状态下心率及各项中医症状体征评分与治疗前比较,差异均具有统计学意义(P<0.05)。A组治疗后愈显率和总有效率分别为14.3%和85.7%,B组分别为82.4%和100.0%,C组分别为85.3%和100.0%。B组和C组治疗后各项甲状腺激素水平、静息状态下心率、各项中医症状体征评分及愈显率与A组比较,差异均具有统计学意义(P<0.05)。结论针刺配合药物是一种治疗原发性甲亢的有效方法,每周针刺治疗2次与3次的疗效相当,均优于每周治疗1次。Objective To observe and compare the clinical efficacies of acupuncture at different time intervals plus medication for primary hyperthyroidism.Method One hundred and eleven patients with primary hyperthyroidism were randomized to groups A,B and C,with 37 cases in each group.All the three groups received acupuncture plus oral administration of Methimazole tablets.Group A was treated with acupuncture once a week;group B,twice a week;group C,thrice a week.Thyroxine[thyroid stimulating hormone(TSH),free triiodothyronine(FT3)and free tetraiodothyronine(FT4)]levels and resting heart rate were measured and TCM symptom and sign item scores were recorded in the thhree groups before and after 24 weeks of treatment.The clinical therapeutic effects were compared among the three groups.Result Thyroxine item levels,resting heart rate and TCM symptom and sign item scores had pre-/post-treatment statistical significant differences in the three groups(P<0.05).The cure-marked efficacy rate and the total efficacy rate were 14.3%and 85.7%,respectively,in group A;82.4%and 100.0%,respectively,in group B;85.3%and 100.0%,respectively,in group C.Thyroxine item levels,resting heart rate,TCM symptom and sign item scores and the cure-marked efficacy rate had post-treatment statistical significant differences between groups B and C and group A(P<0.05).Conclusion Acupuncture plus medication is an effective ways to treat primary hyperthyroidism.Acupuncture treatment twice and thrice a week have an equivalent effect but they are better than treatment once a week.

关 键 词：针刺疗法 甲状腺功能亢进症 颤针 治疗频次 针药并用 

分 类 号：R246.1[医药卫生—针灸推拿学]