静脉注射丙种球蛋白无反应性川崎病的高危因素分析  

Risk factors of children with Kawasaki disease resistant to intravenous immunoglobulin

作　　者：杨成洋 范雪 徐明国 Yang Chengyang;Fan Xue;Xu Mingguo(Medical College,Shantou University,Shantou 515000,China)

机构地区：[1]汕头大学医学院,汕头515000

出　　处：《国际医药卫生导报》2023年第10期1358-1360,共3页International Medicine and Health Guidance News

摘　　要：川崎病是一种好发于儿童的急性全身性血管炎性疾病。目前,大剂量静脉注射丙种球蛋白联合口服阿司匹林是川崎病的标准治疗方案,但临床上存在一部分对静脉注射丙种球蛋白不敏感的病例。此类患者容易形成冠状动脉动病变,严重时可能导致心肌梗死和死亡。本文主要综述静脉注射丙种球蛋白无反应性川崎病的相关高危因素。Kawasaki disease is an acute systemic vasculitic disease that tends to occur in children.At present,high-dose intravenous immunoglobulin combined with oral aspirin is the standard treatment for Kawasaki disease,but some cases are not sensitive to intravenous immunoglobulin clinically.Such patients are prone to coronary artery lesions,which may lead to myocardial infarction and death in severe cases.This article mainly reviews the risk factors of children with Kawasaki disease resistant to intravenous immunoglobulin.

关 键 词：川崎病 高危因素 儿童 

分 类 号：R725.4[医药卫生—儿科]