“卫气营血”理论辨证防治急性肺损伤研究现状  

Research status of dialectical prevention and treatment of acute lung injury based on the theory of"Wei qi and Ying Xue"

作　　者：齐晓风 骆亚莉 肖孟勇[1] 周世琴 周雯 安方玉 魏本君 刘永琦 QI Xiaofeng;LUO Yali;XIAO Mengyong;ZHOU Shiqin;ZHOU Wen;AN Fangyu;WEI Benjun;LIU Yongqi(Gansu University of Chinese Medicine,Provincial Key Laboratory of Molecular Medicine and TCM for the Prevention and Treatment of Major Diseases in Colleges and Universities of Gansu Province,Gansu 730000,Lanzhou,China;Gansu University of Chinese Medicine,Key Laboratory of Chronic Diseases for Prevention and Treatment of Traditional Chinese Medicine of Gansu Province,Gansu 730000,Lanzhou,China)

机构地区：[1]甘肃中医药大学,甘肃省高校重大疾病分子医学与中医药防治研究省级重点实验室,兰州甘肃730000 [2]甘肃中医药大学,甘肃省中医药防治慢性疾病重点实验室,兰州甘肃730000

出　　处：《中国临床药理学与治疗学》2023年第4期429-437,共9页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：国家自然科学基金(82160846);甘肃省科技厅自然科学基金项目(20JR10RA321);甘肃省教育厅高等学校创新基金(2021A-085);甘肃省“双一流”科研重点项目(GSSYLXM-05)。

摘　　要：急性肺损伤(ALI)是临床常见危重型呼吸系统疾病。目前该病机制尚未完全阐明,临床上缺乏特效药且致死率高,是医学领域的难题。近年来,传统中医药在防治ALI发挥出其独特的优势和功效,引起国内外学者关注。本文基于“卫气营血”理论探讨中医药防治ALI的研究现状,就其发病机制、临床表现等与中医病证对应分析。研究发现按“卫气营血”角度展开辨证论治,其发病进展与免疫应答、炎症反应、氧化应激和细胞凋亡等环节高度一致,可为临床中西医结合防治ALI寻找新的思路与用药。Acute lung injury(ALI)is a common clinical critical respiratory disease.At present,the mechanism of the disease has not been fully elucidated,there is a lack of specific drugs in clinical practice and the mortality rate is high,which is a difficult problem in the medical field.In recent years,traditional Chinese medicine has exerted its unique advantages and efficacy in the prevention and treatment of ALI,which has aroused the attention of domestic and foreign scholars.Based on the theory of"Wei Qi Ying Xue",this paper discusses the current research status of prevention and treatment of ALI by traditional Chinese medicine, andanalyzes its pathogenesis, clinical manifestationsand corresponding analysis with TCM syndrome.According to the angle of "Wei Qi Ying Xue", theprogress of syndrome differentiation and treatmentis highly consistent with immune response,inflammatory response, oxidative stress and apoptosis,in order to find new ideas and medication forthe prevention and treatment of ALI with integratedtraditional Chinese and Western medicine.

关 键 词：急性肺损伤 卫气营血 中医药 暴喘 

分 类 号：R563[医药卫生—呼吸系统] R28[医药卫生—内科学]