恶性肿瘤麻醉手术中应用异丙酚静脉麻醉与七氟醚吸入麻醉的效果对比  

Effect of Propofol Intravenous Anesthesia and Sevoflurane Inhalation Anesthesia in Anesthesia Surgery of Malignant Tumors

作　　者：徐效标 刘胜群 XU Xiaobiao;LIU Shengqun(Department of Anesthesiology,Zhecheng People's Hospital,Shangqiu 476200,Henan,China)

机构地区：[1]柘城县人民医院麻醉科,河南商丘476200

出　　处：《中国药物滥用防治杂志》2023年第3期397-400,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:比较恶性肿瘤手术中应用异丙酚静脉麻醉与七氟醚吸入麻醉的效果。方法:选择2018年2月—2019年12月我院就诊的88例恶性肿瘤患者作为研究对象,按照随机数字表法分为对照组和观察组,每组44例。对照组术予以异丙酚静脉麻醉,观察组予以七氟醚吸入麻醉,比较两组不同时间段[麻醉前(T_(1))、插管后(T_(2))、手术开始时(T_(3))、手术结束(T_(4))]血压和心率变化情况、麻醉效果(苏醒时间、拔管时间和手术治疗)及麻醉手术后产生的不良反应情况。结果:两组T_(1)时血压、心率值比较,差异无统计学意义(P>0.05),而观察组T_(2)、T_(3)、T_(4)时血压和心率优于对照组(P<0.05);观察组苏醒时间、手术治疗时间和拔管时间短于对照组(P<0.05);观察组不良反应发生率为6.82%,低于对照组的25.00%(P<0.05)。结论:在恶性肿瘤手术治疗中采取七氟醚吸入麻醉的临床效果好,麻醉副作用少,能维持其稳定的生命体征,值得临床借鉴使用。Objective:To compare the anesthesia effect of propofol intravenous anesthesia and sevoflurane inhalation anesthesia in malignant tumor surgery.Methods:A total of 88 patients with malignant tumors who were treated in our hospital from February 2018 to December 2019 were selected as the research objects,and divided into the control group and the observation group according to the random number table method,with 44 cases in each group.The control group was given propofol intravenous anesthesia during operation,and the observation group was given sevoflurane inhalation anesthesia.The changes of blood pressure and heart rate at diferent time periods[before anesthesia(T_(1)),after intubation(T_(2)),at the beginning of operation(T_(3))and at the end of operation(T_(4))],anesthesia effect(recovery time,extubation time and surgical treatment)and adverse reactions after anesthesia were compared between the two groups.Results:There was no significant difference in blood pressure and heart rate at T,between the two groups(P>0.05),while the blood pressure and heart rate at T_(2),T_(3)and T_(4)in the observation group were better than those in the control group(P<0.05).The recovery time,operation treatment time and extubation time in the observation group were shorter than those in the control group(P<0.05).The incidence of adverse reactions in the observation group was 6.82%,which was lower than 25.00%in the control group(P<0.05).Conclusion:The use of sevoflurane inhalation anesthesia in the surgical treatment of malignant tumors has a good clinical effect,has less side effects of anesthesia,and can maintain stable vital signs in patients,which is worthy of clinical reference.

关 键 词：异丙酚静脉麻醉 七氟醚吸入麻醉 恶性肿瘤 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]