慢性阻塞性肺疾病合并焦虑抑郁的危险因素及发病机制研究进展  

Research progress on risk factors and pathogenesis of chronic obstructive pulmonary disease complicated with anxiety or depression

作　　者：牟鈃雨 徐娇 张林[1] 杨宇豪 曾庆跃 刘思敏 秦羽 李双庆[1] 苏巧俐[1] MU Xingyu;XU Jiao;ZHANG Lin;YANG Yuhao;ZENG Qingyue;LIU Simin;QIN Yu;LI Shuangqing;SU Qiaoli(General Practice Medical Center,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)

机构地区：[1]四川大学华西医院全科医学中心,成都610041

出　　处：《华西医学》2023年第4期591-596,共6页West China Medical Journal

基　　金：四川省科学技术厅项目(2021YFH0168)。

摘　　要：慢性阻塞性肺疾病(慢阻肺)常合并焦虑或抑郁,焦虑抑郁的加重会导致慢阻肺病情恶化,降低患者生活质量,加重不良预后,增加死亡风险。焦虑抑郁是慢阻肺患者死亡的重要原因之一,但其危险因素及发病机制的复杂性常导致临床医师无法及时作出准确的诊断和治疗。该文基于现有的研究,阐述了慢阻肺合并焦虑抑郁的危险因素和发病机制,旨在提高临床医师对慢阻肺合并焦虑抑郁的诊治能力,达到及时诊断与治疗、改善患者预后和提高生活质量的目的。Chronic obstructive pulmonary disease is often accompanied by anxiety or depression.The exacerbation of anxiety and depression can lead to the deterioration of chronic obstructive pulmonary disease,reduce patients'quality of life,worsen poor prognosis,and increase the risk of death.Anxiety and depression are one of the important causes of death in patients with chronic obstructive pulmonary disease,but the complexity of their risk factors and pathogenesis often lead to clinicians being unable to make accurate diagnosis and treatment in a timely manner.Based on existing research,this article elaborates on the risk factors and pathogenesis of chronic obstructive pulmonary disease complicated with anxiety or depression,aiming to improve the diagnosis and treatment ability of clinical physicians for chronic obstructive pulmonary disease complicated with anxiety or depression,achieve timely diagnosis and treatment,improve patients'prognosis,and improve quality of life.

关 键 词：慢性阻塞性肺疾病 焦虑 抑郁 危险因素 发病机制 

分 类 号：R563.9[医药卫生—呼吸系统] R749[医药卫生—内科学]