血清尿酸水平与妊娠期高血压疾病相关性研究进展  

Research progress on the relationship between serum uric acid level and hypertensi disorder of pregnancy

作　　者：张秀颖 张蛟[2] 韩延华[3] 姜玥[3] 张跃辉[3] ZHANG Xiuying;ZHANG Jiao;HAN Yanhua;JIANG Yue;ZHANG Yuehui(First School of Clinical Medicine,Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China;Guoyi Hall,Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China;Department of Gynaecology,First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China)

机构地区：[1]黑龙江中医药大学第一临床医学院,哈尔滨150040 [2]黑龙江中医药大学附属第二医院国医堂,哈尔滨150040 [3]黑龙江中医药大学附属第一医院妇一科,哈尔滨150040

出　　处：《华西医学》2023年第4期621-625,共5页West China Medical Journal

基　　金：国家自然科学基金(82074259);中华中医药学会团体标准项目(20220602-BZ-CACM);黑龙江中医药大学杰出人才基金(2018jc02);黑龙江中医药大学优秀青年学术带头人支持计划。

摘　　要：妊娠期高血压疾病(hypertensive disorder of pregnancy, HDP)是妊娠期妇女特有的一类疾病,临床最常见类型是妊娠期高血压和子痫前期,这类疾病严重威胁孕产妇和胎儿的健康。目前,对于HDP的预测和防治并没有确定标准。近年来全球对HDP进行了大量研究,众多研究显示血清和HDP之间有较为密切的相关性。该文通过对现有文献研究结果进行综述,阐述血清尿酸与HDP发病机制、预测HDP发生发展和不良妊娠结局等方面的相关性。Hypertensive disorder of pregnancy(HDP)is a type of disease unique to women during pregnancy.The most common clinical types are gestational hypertension and preeclampsia,which seriously threaten the health of pregnant women and fetuses.At present,there are no established criteria for the prediction and prevention of HDP.In recent years,a large number of studies have been carried out on HDP around the world,and many studies have shown a close correlation between serum uric acid and HDP.This article reviews the results of existing literature,elucidates the relationship between serum uric acid and the pathogenesis of HDP,prediction of HDP occurrence and development,and adverse pregnancy outcomes.

关 键 词：妊娠期高血压疾病 血清尿酸 子痫前期 

分 类 号：R714.246[医药卫生—妇产科学]