乳腺钼靶、选择性乳腺导管造影及高频彩超在乳头溢液中的诊断价值分析  

The diagnostic value of mammography,selective mammary ductography and high-frequency color Doppler ultrasound in nipple discharge

作　　者：裴长志 林华云 顾英翠 吴慧菊 PEI Chang-zhi;LIN Hua-yun;GU Ying-cui(Heyuan Maternal and Child Health Hospital,Heyuan 517000,China)

机构地区：[1]广东省河源市妇幼保健院,517000

出　　处：《中国现代药物应用》2023年第8期18-21,共4页Chinese Journal of Modern Drug Application

基　　金：2016年河源市社会发展科技计划项目(项目编号:河科[2016]56号-59)。

摘　　要：目的探讨乳腺钼靶、选择性乳腺导管造影、高频彩超在乳头溢液中的诊断价值。方法180例乳头溢液患者,依次进行乳腺钼靶、选择性乳腺导管造影、高频彩超检查。统计分析不同检查方法的诊断结果,以病理诊断作为金标准,比较乳腺钼靶、选择性乳腺导管造影、高频彩超及选择性乳腺导管造影联合高频彩超对乳头溢液的诊断效能(准确度、敏感性、特异性)。结果180例乳头溢液患者中,经手术病理诊断确诊为恶性82例,良性98例。乳腺钼靶检查结果与病理诊断结果的一致性一般(K=0.314)。选择性乳腺导管造影检查结果与病理诊断结果的一致性好(K=0.730)。高频彩超检查结果与病理诊断结果的一致性很好(K=0.873)。乳腺钼靶的诊断敏感性、特异性及准确度分别为68.29%(56/82)、71.43%(70/98)、70.00%(126/180),选择性乳腺导管造影的诊断敏感性、特异性及准确度分别为89.02%(73/82)、83.67%(82/98)、86.11%(155/180),高频彩超的诊断敏感性、特异性及准确度分别为95.12%(78/82)、91.84%(90/98)、93.33%(168/180),选择性乳腺导管造影联合高频彩超的诊断敏感性、特异性及准确度分别为100.00%(82/82)、98.98%(97/98)、99.44%(179/180)。选择性乳腺导管造影、高频彩超单独诊断及联合诊断的敏感性、特异性及准确度均高于乳腺钼靶,高频彩超诊断的准确度高于选择性乳腺导管造影,选择性乳腺导管造影联合高频彩超诊断的敏感性、特异性及准确度均高于选择性乳腺导管造影、高频彩超单独诊断,差异有统计学意义(P<0.05)。结论在乳头溢液的临床诊断中,高频彩超、选择性乳腺导管造影的诊断准确度高于单用乳腺钼靶检查,高频彩超联合选择性乳腺导管造影对临床诊疗价值更高,有助于指导临床治疗。Objective To discuss the diagnostic value of mammography,selective mammary ductography and high-frequency color Doppler ultrasound in nipple discharge.Methods 180 patients with nipple discharge underwent mammography,selective mammary ductography and high-frequency color Doppler ultrasound in order.The diagnostic results of different examination methods were statistically analyzed,and the diagnostic efficacy(accuracy,sensitivity and specificity)of mammography,selective mammary ductography,high-frequency color Doppler ultrasound,and selective mammary ductography combined with high-frequency color Doppler ultrasound on nipple discharge was compared with pathological diagnosis as the gold standard.Results Among 180 patients with nipple discharge,82 cases were malignant and 98 cases were benign.The results of mammography and pathological diagnosis were generally consistent(K=0.314).The results of selective mammary ductography were in good consistency with pathological diagnosis(K=0.730).The results of high-frequency color ultrasound were in very good consistency with the pathological diagnosis(K=0.873).The diagnostic sensitivity,specificity and accuracy of mammography were 68.29%(56/82),71.43%(70/98)and 70.00%(126/180);the diagnostic sensitivity,specificity and accuracy of selective mammary ductography were 89.02%(73/82),83.67%(82/98)and 86.11%(155/180);the diagnostic sensitivity,specificity and accuracy of high-frequency color Doppler ultrasound were 95.12%(78/82),91.84%(90/98)and 93.33%(168/180);the diagnostic sensitivity,specificity and accuracy of selective mammary ductography combined with high-frequency color Doppler ultrasound were 100.00%(82/82),98.98%(97/98)and 99.44%(179/180).The sensitivity,specificity,and accuracy of selective mammary ductography,high-frequency color Doppler ultrasound alone and in combination were higher than those of mammography;the diagnostic accuracy of high-frequency color Doppler ultrasound was higher than that of selective mammary ductography;the sensitivity,specificity,and accuracy

关 键 词：乳头溢液 乳腺钼靶 高频彩超 选择性乳腺导管造影 

分 类 号：R655.8[医药卫生—外科学]