基于金纳米颗粒/壳聚糖/还原氧化石墨烯修饰电极检测岩白菜素  

The detection of bergenin based on the gold nanoparticles/chitosan/reduced graphene oxide modified electrode

作　　者：王晓丹 王诗伟 张娜[2] WANG Xiaodan;WANG Shiwei;ZHANG Na(Department of Mining and Metallurgical Engineering,Baiyin Institute of Mining and Metallurgy,Baiyin 730900,China;Key Laboratory of Spin Electron and Nano-materials of Anhui Higher Education Institues,School of Chemistry and Chemical Engineering,Suzhou University,Suzhou 234000,China)

机构地区：[1]白银矿冶职业技术学院矿冶工程学院,白银730900 [2]宿州学院化学与化工学院,自旋电子与纳米材料安徽普通高校重点实验室,宿州234000

出　　处：《分析试验室》2023年第4期492-495,共4页Chinese Journal of Analysis Laboratory

基　　金：甘肃省高等学校创新基金项目(2021B-546);宿州学院校重点项目(2020yzd10);委托研发项目(2021xhx116,2022xhx019)资助。

摘　　要：制备了金纳米颗粒/壳聚糖/还原氧化石墨烯修饰电极,研究了岩白菜素在修饰电极上的电化学行为,结果表明修饰电极对岩白菜素的氧化具有明显的电催化作用。在0.1 mol/L磷酸盐缓冲溶液(pH 6.0)中,采用示差脉冲伏安法对岩白菜素进行测定,岩白菜素的氧化峰电流与其浓度在2.0×10^(-7)~1.2×10^(-6)mol/L范围内呈良好的线性关系,检出限为6.0×10^(-8)mol/L(S/N=3)。制备的修饰电极具有很好的抗干扰能力,在岩白菜素的实际检测中具有潜在的应用价值。Gold nanoparticles(AuNPs)/chitosan(CS)/reduced graphene oxide(RGO)modified electrode was prepared.The electrochemical behaviors of bergenin on this modified electrode was investigated by cyclic voltammetry.The results showed that the proposed electrode exhibited an obvious electrocatalytic ability to the oxidation of bergenin.The differential pulse voltammetry was employed to detect bergenin in 0.1 mol/L phosphate buffer solution(pH 6.0).A good linear relationship between the oxidation peak current and the concentration of bergenin was found in the range of 2.0×10^(-7)-1.2×10^(-6)mol/L with the detection limit of 6.0×10^(-8)mol/L(S/N=3).The prepared electrode had good anti-interference ability and potential application in the actual detection of bergenin.

关 键 词：岩白菜素:金纳米颗粒 石墨烯 修饰电极 

分 类 号：R446[医药卫生—诊断学]