紫菀的研究进展及质量标志物预测分析  

Advances in Studies on Asteris Radix et Rhizoma and Prediction of Its Quality Markers

作　　者：韩杨杨 高凡 秦飘然 白然 田佳业 刘兴超 袁骢冲 郭秋红[1] HAN Yang-yang;GAO Fan;QIN Piao-ran;BAI Ran;TIAN Jia-ye;LIU Xing-chao;YUAN Cong-chong;GUO Qiu-hong(Hebei University of Chinese Medicine,Shijiazhuang 050200,China;Hebei Academy of Chinese Medical Sciences,Shijiazhuang 050031,China;State Key Laboratory of Dao-di Herbs,Beijing 100700,China)

机构地区：[1]河北中医学院,石家庄河北050200 [2]河北省中医药科学院,石家庄河北050031 [3]道地药材国家重点实验室,北京100700

出　　处：《中国现代中药》2023年第3期655-664,共10页Modern Chinese Medicine

基　　金：中央本级重大增减支项目(2060302);河北省重点研发计划项目(20373001D)。

摘　　要：紫菀是临床常用的化痰止咳要药,始载于《神农本草经》。紫菀化学成分丰富,主要包括萜类及其苷、肽类、黄酮、蒽醌、香豆素、有机酸、酚类、甾醇、挥发油及苯丙素类等。现代药理学研究表明,紫菀在抗肿瘤、抗病毒、抗氧化等方面也具有显著的药理活性。对紫菀的资源分布、化学成分、药理活性研究进展进行综述,并依据质量标志物的概念及确定原则对紫菀的质量标志物进行预测分析,以期为紫菀质量标准的深入研究提供参考。Asteris Radix et Rhizoma is a common clinical medicine first recorded in Shen Nong's Herbal Classic for expelling phlegm and relieving cough.Asteris Radix et Rhizoma has abundant chemical constituents,with terpenoids,glycosides,peptides,flavonoids,anthraquinones,coumarins,organic acids,phenols,sterols,volatile oils and phenylpropanoids being the most prevalent components.Modern pharmacological studies have shown that Asteris Radix et Rhizoma also has significant pharmacological activities,such as anti-tumor,antiviral,antioxidant,and other activities.This review focused on the research progress in the resource distribution,chemical composition,and pharmacological activities of Asteris Radix et Rhizoma.Moreover,the quality markers of Asteris Radix et Rhizoma were predicted and analyzed in accordance with the concepts and determination principles of quality markers.These results may provide a reference for indepth studies on quality criteria of Asteris Radix et Rhizoma.

关 键 词：紫菀 紫菀酮 质量标志物 化学成分 药理活性 

分 类 号：R282.71[医药卫生—中药学]