分析首发症状为酮症酸中毒的糖尿病患儿中毒抢救、临床特点以及诊治  

To Analyze the Rescue,Clinical Characteristics,Diagnosis and Treatment of Children with Diabetes whose First Symptom was Ketoacidosis

作　　者：舒红斌 刘利 SHU Hongbin;LIU Li(Department of Pediatrics,Xiaochang County First People's Hospital,Xiaochang,Hubei Province,432900 China)

机构地区：[1]湖北省孝昌县第一人民医院儿科,湖北孝昌432900

出　　处：《糖尿病新世界》2023年第3期174-177,共4页Diabetes New World Magazine

摘　　要：目的分析糖尿病患儿的酮症酸中毒为首发症状中毒的抢救、诊治、临床特点。方法选取2019年1月—2021年12月湖北省孝昌县第一人民医院儿科收治的75例行抢救治疗的首发症状为酮症酸中毒的糖尿病患儿为研究对象,按照抢救方式分为常规组(n=37)和观察组(n=38)。常规组患儿接受常规抢救措施,观察组患儿在常规组基础上加用小剂量胰岛素治疗,比较两组患儿的治疗效果、生化指标、血糖水平、胰岛素水平、并发症发生率。结果观察组患儿疗效高于常规组,差异有统计学意义(P<0.05);观察组患儿血浆黏度、血细胞比容、纤维蛋白原、高切全血黏度、三酰甘油、总胆固醇、低密度脂蛋白胆固醇均低于常规组,差异有统计学意义(P<0.05);观察组患儿血糖水平低于常规组,差异有统计学意义(P<0.05);观察组患儿胰岛素水平低于常规组,差异有统计学意义(P<0.05);观察组患儿不良反应及并发症发生率低于常规组,差异有统计学意义(P<0.05)。结论酮症酸中毒为首发症状的糖尿病患儿有着多种临床特征,需要采取补液、补钾等治疗,同时加用胰岛素降血糖是能够提高治疗效果。Objective To analyze the rescue,diagnosis and treatment,clinical characteristics of diabetic children with ketoacidosis as the first symptom poisoning.Methods 75 diabetic children with the first symptom of ketoacidosis treated with rescue treatment admitted to the pediatrics of the First People's Hospital of Xiaochang County,Hubei Province from January 2019 to December 2021 were selected as the research objects and divided into conventional group(n=37)and observation group(n=38)according to rescue methods.The children in the conventional group received conventional rescue measures,and the children in the observation group were treated with low-dose insulin on the basis of the conventional group.The therapeutic effect,biochemical indexes,blood glucose level,insulin level and complication rate of the two groups were compared.Results The curative effect of observation group was higher than that of conventional group,the difference was statistically significant(P<0.05).The plasma viscosity,hemocytometry volume,fibrinogen and high cut whole blood viscosity,while the triglyceride,total cholesterol and low density lipoprotein cholesterol in observation group were lower than those in conventional group,the difference was statistically significant(P<0.05).The blood glucose level in the observation group was lower than that in the conventional group,the difference was statistically significant(P<0.05).The insulin level in observation group was lower than that in conventional group,the difference was statistically significant(P<0.05).The incidence of adrerse reactions and complications in observation group was lower than that in conventional group,the difference was statistically significant(P<0.05).Conclusion Children with diabetes with ketoacidosis as the first symptom have a variety of clinical characteristics,and need to take fluid supplement,potassium supplement and other treatments.At the same time,the addition of insulin to reduce blood glucose can improve the therapeutic effect.

关 键 词：糖尿病 酮症酸中毒 抢救 临床特点 诊治 

分 类 号：R72[医药卫生—儿科]