巨型脐膨出手术治疗策略与远期预后研究进展  

Research advances in surgical strategies for giant omphalocele and its long-term outcomes

作　　者：朱维娜 沈淳[1] 朱海涛[1] Zhu Weina;Shen Chun;Zhu Haitao(Department of Pediatric Surgery,Children's Hospital of Fudan University,National Children's Medical Center,Shanghai 201102,China)

机构地区：[1]国家儿童医学中心,复旦大学附属儿科医院新生儿外科,上海201102

出　　处：《中华小儿外科杂志》2023年第4期370-376,共7页Chinese Journal of Pediatric Surgery

基　　金：上海市科技创新行动计划医学创新研究专题项目(20Y11906900);复旦大学附属儿科医院多学科诊疗(MDT)拔尖项目(第二期,复旦儿科-2020)。

摘　　要：巨型脐膨出(giant omphalocele,GO)依然是目前威胁新生儿生命健康的严重先天畸形之一。GO由于腹壁缺损巨大,往往无法一期手术治愈,有效治疗手段也十分有限,且GO常合并其他畸形,远期预后不佳。近年来各种分期手术及延期手术治疗策略有效提高GO治疗成功率并改善GO患儿预后,本文将就目前GO主要的手术治疗策略及其远期预后研究进展进行综述,为临床GO手术方案的选择提供参考。Giant Omphalocele(GO)is one of life-threatening congenital defects during neonatal period.Immediate primary repairing often fails due to its massive sac.Its long-term prognosis remains poor because of limited therapeutic strategies and associated anomalies.Recently various staged and delayed surgical strategies have improved GO outcomes significantly.This review offered a latest summary of diverse operative options and prognoses to provide references for selecting various procedures.

关 键 词：疝 脐 脐膨出 分期性手术 远期预后 

分 类 号：R726.5[医药卫生—儿科]